...BRCA1 and BRCA2 mutation spectrum and the frequencies of deleterious alleles in various ethnic groups; (2) investigation...
Germline mutations in the BRCA1 tumor suppressor gene often result in a significant increase in susceptibility to breast...
The BRCT repeats in BRCA1 are essential for its tumor suppressor activity and interact with phosphorylated protein targe...
The study aimed to determine whether hereditary ovarian cancers that are not caused by BRCA1/BRCA2 constitutional mutati...
...BRCA1 and BRCA2 in high-risk non-Ashkenazi Jews. In a Libyan family the 1100delAT BRCA1 mutation was detected and the 87...
...BRCA1 gene, using combined DGGE and direct sequencing. For haplotype analysis, six polymorphic markers were used for all...
To examine the short-term psychological impact of receiving definite results concerning BRCA1 mutation status in a clini...
...BRCA1 or -2 mutation, but it is important to screen high-risk women at least annually and possibly under 35 years.
...BRCA1 or BRCA2 compared with 28 (1.9%) controls. After adjusting for age, the presence of a BRCA1 or BRCA2 mutation was ...
...Brca1 results in cellular demise or tumorigenesis depending on cellular context. Inactivation of p53 contributes to Brca...
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