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Brap2 functions as a cytoplasmic retention protein for p21 during monocyte di...

Asada(Minoru),Ohmi(Kazuhiro),Delia(Domenic... Mol Cell Biol 2004-10-07

...BRCA1 and was recently reported to inactivate KSR in the Ras-activating signal pathway under the name of IMP. We report ...

Evaluation of psychosocial effects of pre-symptomatic testing for breast/ovar...

Arver(Brita),Haegermark(Aina),Platten(Ulla... Fam Cancer 2004-11-26

...BRCA1, BRCA2, MLH1, and MSH2 was performed. Eighty-seven healthy women were tested for known family mutations and self-a...

Analysis of missense variation in human BRCA1 in the context of interspecific...

Abkevich(V),Zharkikh(A),Deffenbaugh(A M),F... J Med Genet 2004-12-21

...BRCA1, BRCA2, MLH1, MSH2, TP53, and PTEN, is becoming an increasingly important part of clinical practice. Interpretatio...

BRCA1 is required for common-fragile-site stability via its G2/M checkpoint f...

Arlt(Martin F),Xu(Bo),Durkin(Sandra G),Cas... Mol Cell Biol 2004-08-16

...BRCA1 plays a key role. Furthermore, they suggest that mutations in BRCA1 or interacting proteins could lead to rearrang...

Genetic testing for breast and ovarian cancer susceptibility: evaluating dire...

MMWR Morb Mortal Wkly Rep 2004-07-21

...BRCA1 and BRCA2 (BRCA1/2), are associated with predisposition for inherited breast and ovarian cancer and are identified...

Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintain...

Nakamura(Toru M),Du(Li-Lin),Redon(Christop... Mol Cell Biol 2004-09-03

...BRCA1 carboxyl terminus domain-containing proteins (NBS1, 53BP1, MDC1/NFBD1, and BRCA1) in mammals.

Organization of mammary epithelial cells into 3D acinar structures requires g...

Murtagh(Janice),McArdle(Emmett),Gilligan(E... J Cell Biol 2004-08-26

...BRCA1, GADD45beta, MEKK4, and the JNK activating complex GADD 45beta-MEKK4 in a glucocorticoid-dependent fashion. JNK ca...

No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 an...

Campbell(Ian G),Choong(David),Chenevix-Tre... Breast Cancer Res 2004-11-04

Mutations in BRCA1, BRCA2, ATM, TP53, CHK2 and PTEN account for many, but not all, multiple-case breast and ovarian canc...

Frequency of the ATM IVS10-6T-->G variant in Australian multiple-case breast ...

Lindeman(Geoffrey J),Hiew(Melody),Visvader... Breast Cancer Res 2004-11-04

...BRCA1 mutation and one patient had a BRCA1 unclassified variant of uncertain significance.,These findings indicate that ...

Fanconi anaemia and leukaemia - clinical and molecular aspects.

Tischkowitz(Marc),Dokal(Inderjeet) Br J Haematol 2004-08-31

...BRCA1 and BRCA2. This review summarizes the general clinical and specific haematological features and the current manage...

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