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Smyczynska(U),Rycerz(A),Kozlowska(K),Symec... Biomark Res 2026-01-09

...BRCA1/2 pathogenic variants, from three centers were collected. MiRNAs were quantified using miRNA sequencing (miRNA-seq...

Alzogaray(V) Clin Genet 2026-06-00

...BRCA1/2 variants accounted for 25% of positive cases, while 61.5% involved non-BRCA genes (ATM, RAD51C, MUTYH). No recur...

Diab(E),Roussel-Simonin(C),Giugliano(F),Di... Breast 2026-02-00

...BRCA1 (22 %), RB1 (17 %). PTEN mutations were more frequent among YA with TNBC than older patients (26 % vs 8 %; p = 0.0...

Gamble(A),Ward(TA),Wheeler(OPG),Morris(JP)... Mol Cell 2026-01-22

...BRCA1 and BRCA2. IFI16 acts directly at stalled replication forks to protect nascent DNA from degradation by the nucleas...

Vlachos(G),Moser(T),Lazzeri(I),Moser(MJ),G... Br J Cancer 2026-03-00

...BRCA1/2 mutation testing or genomic scars, fail to capture the full spectrum of HRD. Tissue-based testing is further ham...

Huz(M),Karadag Soylu(N),Koc(A),Kucukakcali... Diagnostics (Basel) 2026-01-04

...BRCA1) in HBV-HCC and cryptogenic hepatocellular carcinoma (Cr-HCC) cases. Methods: The study groups consisted of HBV-HC...

Baskar(S),Patel(RR),Gao(MT),Rose(BE),Bawek... Eur J Cancer 2026-02-05

...BRCA1/2, ATM), and mismatch repair (MMR) genes, which may have potential therapeutic implications. Targeted therapies ha...

Oswald(AJ),Hollis(RL),Churchman(M),Croy(I)... Sci Rep 2026-01-10

...BRCA1/2 CNL in both clinical cohorts was poor (BRCA1; 0-11.5%, BRCA2; 10-36.8%). There was frequent co-occurrence of BRC...

Tomas(EJ),Davis(J),Ramos Valdes(Y),Shepher... Cancer Biol Ther 2026-12-31

...BRCA1/2-mutated HGSC, and niraparib is approved for platinum-sensitive recurrent disease. However, research is currently...

Parulekar(M),Kim(YN),Kim(K),Lee(S),No(JH),... Gynecol Oncol 2026-02-00

...BRCA1, BRCA2, PALB2, MLH1, MSH2, MSH6, BRIP1, RAD51C, RAD51D, ATM, and CHEK2) with a variant allele frequency (VAF) of ≥...