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TP53 BRCA1 CRISPR single-cell cancer

Butterfield(Andrew),Vedagiri(Vivek),Lang(E... BMC Bioinformatics 2004-06-08

...BRCA1 sequences from 20 mammals, or a 10 species subset. Up to five-fold parallel performance gains over serial were rec...

Boulton(Simon J),Martin(Julie S),Polanowsk... Curr Biol 2004-02-26

...BRCA1 predispose individuals to early onset breast and ovarian cancer. BRCA1 together with its structurally related part...

Abramovitch(S),Werner(H) Horm Metab Res 2004-08-16

...BRCA1 and p53. To assess the potential functional interactions between BRCA1 and p53 in transcriptional control of the I...

Kelly(Patricia) Cancer Nurs 2004-02-04

Hereditary breast cancer and the BRCA1 and BRCA2 genes have received a great deal of publicity over the past few years. ...

Meetei(Amom R),Yan(Zhijiang),Wang(Weidong) Cell Cycle 2004-05-21

...BRCA1 and FANCL(PHF9), have been suggested to be this ligase. Here we found that FANCL, but not BRCA1, evolutionarily co...

Srinivas(Gopal),Annab(Lois A),Gopinath(Gok... Mol Carcinog 2004-02-03

...BRCA1 may normally act as a growth inhibitor in these cells. Also, there are other reports that suggest that wild-type B...

Seal(Sheila),Barfoot(Rita),Jayatilake(Hira... Cancer Res 2004-03-11

...BRCA1/2-negative families, each with at least three cases of breast cancer, for mutations in FANCA, FANCC, FANCD2, FANCE...

Takeda(Motohiro),Ishida(Takanori),Ohnuki(K... Breast Cancer 2004-03-11

BRCA1 and BRCA2 mutations cause high breast cancer incidence rates as high as 80% Although prophylactic therapy is still...

Valarmathi(Mani T),Sawhney(Meenakshi),Deo(... Hum Mutat 2004-03-08

The two major hereditary breast/ovarian cancer predisposition tumor suppressor genes, BRCA1 and BRCA2 that perform appar...

Niell(Bethany L),Rennert(Gad),Bonner(Josep... J Natl Cancer Inst 2004-01-27

...BRCA1 and/or BRCA2 (BRCA1/2) profoundly increase the risks of breast and ovarian cancers, but it is unclear whether muta...

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