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TP53 BRCA1 CRISPR single-cell cancer

Jefford(Charles Edward),Feki(Anis),Harb(Je... Oncogene 2004-06-01

...BRCA1 heterodimer and induction of apoptosis in a BRCA1-independent manner. We have constructed a series of BARD1 deleti...

Tyrer(Jonathan),Duffy(Stephen W),Cuzick(Jack) Stat Med 2004-07-13

...BRCA1 and BRCA2 genes has explained some of the genetic determinants of breast cancer risk, but these genes alone do not...

Bowen(Deborah J),Burke(Wylie),McTiernan(An... Patient Educ Couns 2004-07-07

...BRCA1/2 mutation for breast cancer risk, having no personal history of breast or ovarian cancer, living within 60 miles ...

Choudhury(Atish D),Xu(Hong),Baer(Richard) J Biol Chem 2004-10-25

...BRCA1 gene can account for induction of BRCA1 expression at the G1/S transition, the mechanisms by which BRCA1 is down-r...

Ree(Anne Hansen),Bratland(Ase),Solberg Lan... Anticancer Res 2004-07-19

...BRCA1 genotype of the HCC1937/BRCA1wt cell line was associated with significant down-regulation of PLK mRNA expression a...

Desper(Richard),Khan(Javed),Schäffer(Aleja... J Theor Biol 2004-09-27

...BRCA1 mutations from those with BRCA2 mutations, with sporadic tumors separated from both groups and from each other. We...

Mirkovic(Nebojsa),Marti-Renom(Marc A),Webe... Cancer Res 2004-07-26

The BRCA1 gene from individuals at risk of breast and ovarian cancers can be screened for the presence of mutations. How...

Beger(Carmela),Ramadani(Marco),Meyer(Steph... Clin Cancer Res 2004-12-27

...BRCA1-regular as compared with BRCA1-reduced or BRCA1-absent tumors. In contrast, no substantial differences in BRCA2 ex...

Evans(D G R),Eccles(D M),Rahman(N),Young(K... J Med Genet 2004-09-27

To develop a simple scoring system for the likelihood of identifying a BRCA1 or BRCA2 mutation.,DNA samples from affecte...

Hadjisavvas(Andreas),Charalambous(Elpida),... Cancer Genet Cytogenet 2004-07-13

The entire coding regions of the two breast cancer susceptibility genes BRCA1 and BRCA2 from breast cancer patients from...

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