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The variant E233G of the RAD51D gene could be a low-penetrance allele in high...

Rodríguez-López(Raquel),Osorio(Ana),Ribas(... Int J Cancer 2004-07-16

...BRCA1/2 genes, with a frequency of 5.74% (n = 174) compared to a control population (n = 567) and another subset of brea...

An encephalitozoon cuniculi ortholog of the RNA polymerase II carboxyl-termin...

Hausmann(Stéphane),Schwer(Beate),Shuman(St... Biochemistry 2004-08-11

...BRCA1 carboxyl terminus (BRCT) domain but lacks the large N- and C-terminal domains found in fungal and metazoan Fcp1 en...

Identification and evaluation of 55 genetic variations in the BRCA1 and the B...

Kawahara(Masanori),Sakayori(Masato),Shirai... J Hum Genet 2004-08-24

...BRCA1 and 34 in BRCA2) containing nine pathogenic protein-truncating mutations (four in BRCA1 and five in BRCA2 from ten...

Ethical aspects of genetic screening in Israel.

Sagi(M) Sci Context 2004-05-31

...BRCA1 and BRCA2. The author also explains why geneticists in Israel cooperate with a screening program in the ultra-orth...

Chromosomal mutagen sensitivity associated with mutations in BRCA genes.

Speit(G),Trenz(K) Cytogenet Genome Res 2004-11-01

...BRCA1 mutation in accordance with the proposed central role of BRCA1 in maintaining genomic integrity. Mutations in BRCA...

Possible causes of chromosome instability: comparison of chromosomal abnormal...

Grigorova(M),Staines(J M),Ozdag(H),Caldas(... Cytogenet Genome Res 2004-11-01

...BRCA1 and BRCA2, had very abnormal karyotypes, with many structural and numerical chromosome changes and substantial var...

Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase.

Sato(Ko),Hayami(Ryosuke),Wu(Wenwen),Nishik... J Biol Chem 2004-09-21

...BRCA1-BARD1 both identified NPM. NPM interacts with N-terminal fragments of BRCA1 and BARD1 in a manner dependent upon B...

Refining clinical practice: transforming science research into the art of med...

Chee(Y C) Ann Acad Med Singapore 2004-09-17

...BRCA1 and BRCA2, were found to confer high risks of breast and ovarian cancer on women with these genes. The application...

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 ...

Kitagawa(Risa),Bakkenist(Christopher J),Mc... Genes Dev 2004-07-19

...BRCA1 are required for the recruitment of previously activated ATM to the sites of DNA breaks after ionizing irradiation...

BRCA1/2 predictive testing: a study of uptake in two centres.

Brooks(Lucy),Lennard(Fiona),Shenton(Andrew... Eur J Hum Genet 2004-10-28

...BRCA1 and BRCA2 can largely be accounted for by different methodologies and by studying research vs nonresearch families...

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