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Association of NQO1 polymorphism with spontaneous breast cancer in two indepe...

Menzel(H-J),Sarmanova(J),Soucek(P),Berberi... Br J Cancer 2004-06-16

...BRCA1, N372H in BRCA2, C112R (E4) and R158C (E2) in ApoE and C825T in GNB3, did not show any sign of association. The P1...

Abnormality of the DNA double-strand-break checkpoint/repair genes, ATM, BRCA...

Ding(S L),Sheu(L F),Yu(J C),Yang(T L),Chen... Br J Cancer 2004-06-16

...BRCA1 and TP53, in sporadic breast cancer requires clarification, since ATM and BRCA1 mutations are rare in sporadic tum...

A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer ris...

Kadouri(L),Kote-Jarai(Z),Hubert(A),Duroche... Br J Cancer 2004-06-16

Variation in the penetrance estimates for BRCA1 and BRCA2 mutation carriers suggests that other genetic polymorphisms ma...

BRCA1 inhibits membrane estrogen and growth factor receptor signaling to cell...

Razandi(Mahnaz),Pedram(Ali),Rosen(Eliot M)... Mol Cell Biol 2004-08-04

...BRCA1 (but not mutant BRCA1). E2 induced the synthesis of cyclins D1 and B1, the activity of cyclin-dependent kinases Cd...

Generation and analysis of Brca1 conditional knockout mice.

Deng(Chu-Xia),Xu(Xiaoling) Methods Mol Biol 2004-09-09

...BRCA1 predispose women to breast and ovarian cancers. However, loss-of-function mutations of mouse Brca1 results in rece...

Analysis of cell cycle progression and genomic integrity in early lethal knoc...

Brown(Eric J) Methods Mol Biol 2004-09-09

...BRCA1, BRCA2, or Rad51 leads to developmental arrest prior to gastrulation. While prior to arrest the number of cells ex...

BRCA1 function mediates a TRAP/DRIP complex through direct interaction with T...

Wada(Osamu),Oishi(Hajime),Takada(Ichiro),Y... Oncogene 2004-08-19

...BRCA1 that lack transactivation function. BRCA1 transactivation function was dependent on TRAP220 expression level in a ...

Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.

Metcalfe(Kelly),Lynch(Henry T),Ghadirian(P... J Clin Oncol 2004-06-29

To estimate the risk of contralateral breast cancer in BRCA1 and BRCA2 carriers after diagnosis and to determine which f...

Purification and characterisation of a soluble N-terminal fragment of the bre...

Sturdy(Alice),Naseem(Riffat),Webb(Michelle... J Mol Biol 2004-08-09

The BRCA1 gene encodes a large multidomain protein of 1863 residues, mutations in which lead to breast cancer. Studies t...

Mouse models of human familial cancer syndromes.

Ward(Jerrold M),Devor-Henneman(Deborah E) Toxicol Pathol 2004-10-21

...BRCA1, BRCA2, LKB1, MEN1, MLH, MSH, NF1, TP53, PTEN, RB1, TSC1, TSC2, VHL, and XPA. These lines not only provide models ...

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