The tumor suppressor gene product BRCA1 is a component of the RNA polymerase II (pol II) holoenzyme that is involved, th...
...BRCA1. In sporadic breast cancers the involvement of DNA-repair genes was proved to be dependent on the histological typ...
To detect BRCA1 and BRCA2 gene germline mutation in the Chinese breast cancer families.,Samples of peripheral blood were...
...BRCA1 C-terminal domain functioned as dominant negatives and extended telomeres. Deletion of a novel linker domain of hR...
...BRCA1/2 mutation. Participants were offered free genetic counseling and rapid BRCA1/2 testing. Primary analyses focused ...
...BRCA1/BRCA2 gene-mutation carriers and 60 age-matched women deemed to be at low risk for breast cancer). Mammograms were...
...BRCA1, and c-myc. Moreover, we showed the involvement of other genes important in cell transformation and oxidative stre...
Previous studies have shown that BRCA1-related breast cancers are often high-grade tumors that do not express estrogen r...
...BRCA1 or BRCA2. Here, we set out to confirm these findings in 961 families with non-BRCA1/BRCA2 breast cancer from diver...
...BRCA1 such as CDKN1B, ATR, and RAD51.,The results of this initial study suggest that normal cells from heterozygous BRCA...
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