This study was undertaken to examine transmission of information to first-degree relatives of BRCA1 mutation carriers an...
...BRCA1/2-mutation associated to BC. These data could be useful in the management of HBC. This study includes 17 patients ...
...BRCA1 function, leading to cell cycle arrest and DNA repair. The truncating germline mutation CHEK2(*)1100delC abrogates...
...BRCA1 or BRCA2, with a focus on the cancer sites most relevant to men. Male BRCA1 mutation carriers are at increased ris...
...BRCA1 and BRCA2 (BRCA1/2) mutations are limited, despite the clinical use of this risk-management strategy. Thus, we est...
...BRCA1/2 mutations.,In our model, prophylactic oophorectomy lengthened life expectancy in women with BRCA1/2 mutations, i...
...BRCA1 and in other proteins involved in DNA repair. Here we compare the thermodynamic behavior of the BRCT domains of 53...
...BRCA1, but not BRCA1 bearing specific N-terminal amino acid substitutions, is able to cooperate with BARD1 to increase u...
...BRCA1/2, the BRCA1/2/ models; and performed linear regression analysis to extend the Claus tables with characteristics o...
...BRCA1 or BRCA2 mutation experienced more cancer-related distress than those with a limited family history. Women who had...
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