...NF1, PTCH1, TP53, SMARCB1, SMAD4, KRAS, and ERBB2). Single CTC-targeted NGS detects heterogeneous and shared mutational ...
...NF1 single-nucleotide variant was associated with poor OS (P < 0.0001) and PFS (P = 0.044). In addition, 2 patients with...
...NF1). Across all tumor types, Class 2/3 were enriched for alterations in genes involved in UV response and WNT/β-catenin...
...NF1 were exclusive to MF. Advancing age, higher DIPSS, and poor overall survival (OS) correlated with increased variants...
...NF1-related low-grade neuroglioma. The tumor and peritumoral edema displayed a similar mutation burden, indicating that ...
...NF1) is a common inherited disorder characterized by cutaneous neurofibromas and other features. It is still a challenge...
...NF1. Using a WGS-based classifier, homologous recombination deficiency (HRD) was identified in 2 cases, both presenting ...
...NF1, SHANK3, CHD8 etc.), several high confidence genes were highlighted by a series of functional analyses, including CT...
...NF1), anaplastic lymphoma kinase (ALK) and ROS1 are the main genes that suffer alterations in the tumors of patients wit...
...NF1 in breast cancer, as well as some prognostic markers including TERT in bladder cancer and IDH1 in glioma, were signi...
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