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Age-Associated Genetic Variations in Breast Cancer: Somatic Mutations and Co-Mu…

Ekinci(B),Orenay-Boyacioglu(S),Erdogdu(IH),B… Biomedicines 2026-02-25

...NF1, AR, BRCA2, and KMT2C. Notably, PIK3CA mutations were significantly more frequent in geriatric patients (28.3% vs. 2...

STK11 and DNA Repair Gene Mutations Define Hereditary Subset of Middle Eastern …

Bu(R),Haqawi(W),Razzaq(EAA),Azam(S),Iqbal(K)… Int J Mol Sci 2026-03-14

...NF1. Four patients (36.4%) carried PVs/LPVs in canonical FA pathway genes; this increased to five patients (45.5%) when ...

Real-world outcomes for selumetinib in pediatric patients with neurofibromatosi…

Nishida(Y),Kitajima(A),Ishii(T) Neurooncol Adv None

...NF1) and plexiform neurofibromas (PN) in Japan. The surveillance was initiated on November 16, 2022, the launch date of ...

Pan-cancer analysis of heterogeneity of tumor mutational burden and genomic mut…

Huang(RJ),Huang(YS),An(N),Hu(JJ),Wu(CY),Chen… ESMO Open 2024-07-00

...NF1 in breast cancer, as well as some prognostic markers including TERT in bladder cancer and IDH1 in glioma, were signi...

Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are s…

Kim(HS),Jung(M),Kang(HN),Kim(H),Park(CW),Kim… Oncogene 2017-00-08

...NF1 (9%), KIT (7%) and APC (7%). Mitogen-activated protein kinase (MAPK; 37%), cell cycle (20%) and phosphatidylinositol...

Chromophobe Renal Cell Carcinoma With Extensive Retraction Artifact: A Potentia…

Sangoi(AR),Pivovarcikova(K),Akgul(M),William… Int J Surg Pathol 2025-02-00

...NF1, TP53, FLCN (likely somatic), CHEK2, and ZFHX3 genes. Follow up available in 9 patients showed no evidence of diseas...

Epidemiology and Outcomes of Neurofibromatosis Type 1 (NF-1): Multicenter Terti…

Almuqbil(M),Alshaikh(FY),Altwaijri(W),Baarma… J Multidiscip Healthc 2024-00-00

...NF1 using the revised NIH diagnostic criteria published in 2021 that were registered at the electronic medical records (...

Whole-genome sequencing identifies novel genes for autism in Chinese trios.

Chang(S),Liu(JJ),Zhao(Y),Pang(T),Zheng(X),So… Sci China Life Sci 2024-00-00

...NF1, SHANK3, CHD8 etc.), several high confidence genes were highlighted by a series of functional analyses, including CT...

Lung adenocarcinoma: from molecular basis to genome-guided therapy and immunoth…

Chalela(R),Curull(V),Enríquez(C),Pijuan(L),B… J Thorac Dis 2017-07-00

...NF1), anaplastic lymphoma kinase (ALK) and ROS1 are the main genes that suffer alterations in the tumors of patients wit...

Demographics and Clinical Decision Making in Patients with Germline Moderate Pe…

Ntowe(KW),Thomas(SM),Dalton(JC),Olunuga(E),W… Ann Surg Oncol 2024-10-00

...NF1, RAD51C, RAD51D). Demographics and clinical outcomes were compared. A total of 528 patients met the inclusion criter...

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