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Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction ...

Xia(Yan),Pao(Gerald M),Chen(Hong-Wu),Verma... J Biol Chem 2003-04-30

...BRCA1, which encodes a stable domain containing the RING finger, as well as that of the full-length BRCA1, was significa...

A brief assessment of concerns associated with genetic testing for cancer: th...

Cella(David),Hughes(Chanita),Peterman(Amy)... Health Psychol 2003-02-27

...BRCA1/2 positive, BRCA1/2 negative, panel negative, and true negative. Factor analysis supported the formation of 3 subs...

HER-2/neu status and tumor morphology of invasive breast carcinomas in Ashken...

Quenneville(Louise A),Phillips(Kelly-Anne)... Cancer 2003-01-31

...BRCA1 mutation status is known.,Thirty-eight tumors from 32 BRCA1 carriers and 354 tumors from 334 noncarriers were anal...

Risk factors for ovarian cancer and early-onset breast cancer in Mongolia.

Elit(L),Baigal(G),Jack(E),Munkhtaivan(A),N... Eur J Gynaecol Oncol 2003-03-07

To determine if there are founder BRCA1 mutations in the Mongolian population.,Seventeen women with ovarian cancer, 14 w...

The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origi...

Van Hatten(Ruth A),Tutter(Antonin V),Holwa... J Cell Biol 2003-01-17

...BRCA1 COOH terminus repeat-containing Xmus101 protein is required for loading of Cdc45 onto the origin. Xmus101 chromati...

Control of biochemical reactions through supramolecular RING domain self-asse...

Kentsis(Alex),Gordon(Ronald E),Borden(Kath... Proc Natl Acad Sci U S A 2003-01-14

...BRCA1), and BRCA1-associated RING domain (BARD1), self-assemble into supramolecular structures in vitro that resemble th...

The Fanconi anaemia genome stability and tumour suppressor network.

Bogliolo(M),Cabré(O),Callén(E),Castillo(V)... Mutagenesis 2003-06-17

...BRCA1 and forms discrete nuclear foci. FANCD2 is independently phosphorylated by ATM (the protein whose gene is mutated ...

Structurally distinct modes of recognition of the KIX domain of CBP by Jun an...

Campbell(Kathleen M),Lumb(Kevin J) Biochemistry 2003-01-09

...BRCA1, CREB, c-Jun, c-Myb, p53, papillomavirus E2, and HTLV-1 Tax. Formation of the CREB-CBP complex depends on phosphor...

Expression of a truncated Brca1 protein delays lactational mammary developmen...

Brown(Melissa A),Nicolai(Hans),Howe(Kathy)... Transgenic Res 2003-04-28

...BRCA1 have biological activity in vivo, we have expressed a truncated Brca1 protein (trBrca1) in cell-lines and in the m...

Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its...

Okada(Shinya),Ouchi(Toru) J Biol Chem 2003-02-14

...BRCA1 were employed to study BRCA1 phosphorylation during the S and G2/M phases under conditions of DNA damage. We obser...

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