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Homologous recombination and cell cycle checkpoints: Rad51 in tumour progress...

Henning(Wilhelm),Stürzbecher(Horst Werner) Toxicology 2003-12-16

...BRCA1, BRCA2, BLM and FANCD2 are linked to Rad51-dependent pathways. An increased knowledge of the role of Rad51 in DNA ...

Fallopian tube and primary peritoneal carcinomas associated with BRCA mutations.

Levine(Douglas A),Argenta(Peter A),Yee(Cin... J Clin Oncol 2003-12-10

...BRCA1 and 6174delT in BRCA2). Surgical and pathologic information, family history, and survival data were obtained from ...

The breast cancer low-penetrance allele 1100delC in the CHEK2 gene is not pre...

Osorio(Ana),Rodríguez-López(Raquel),Díez(O... Int J Cancer 2003-12-18

...BRCA1 or BRCA2 genes. In our present study, we evaluated the role of the 1100delC variant as a susceptibility allele in ...

BRCA1 inhibition of telomerase activity in cultured cells.

Xiong(Jingbo),Fan(Saijun),Meng(Qinghui),Sc... Mol Cell Biol 2003-12-16

...BRCA1 (wtBRCA1) but not a tumor-associated mutant BRCA1 (T300G). wtBRCA1 inhibited the expression of the catalytic subun...

Novel consensus DNA-binding sequence for BRCA1 protein complexes.

Cable(P LouAnn),Wilson(Cindy A),Calzone(Fr... Mol Carcinog 2003-10-29

...BRCA1 function in sporadic breast cancers that do not involve germline BRCA1 mutations. The functional specificity of BR...

Phytoestrogen-rich diets modulate expression of Brca1 and Brca2 tumor suppres...

Vissac-Sabatier(Cécile),Coxam(Véronique),D... Cancer Res 2003-12-22

...Brca1 mRNA expression was shown after flax-seed consumption, whereas no variation was noted for Brca2 mRNA, nor for Brca...

Familial breast cancer: an investigation into the outcome of treatment for ea...

Eccles(D),Simmonds(P),Goddard(J),Coultas(M... Fam Cancer 2003-12-16

...BRCA1 mutation carriers were identified through the genetics services in participating centres. These patients were subd...

Double primary cancers of the breast and thyroid in women: molecular analysis...

Pal(T),Hamel(N),Vesprini(D),Sanders(K),Mit... Fam Cancer 2003-11-20

...BRCA1, BRCA2, and PTEN genes. One woman was found to be a carrier of a BRCA1 mutation (exon 11 3227delT). Our findings d...

Does the occurrence of certain rare cancers indicate an inherited cancer susc...

Levene(Sara),Scott(Gillian),Price(Patricia... Fam Cancer 2003-12-16

...BRCA1/BRCA2 (fallopian, young-onset pancreatic) or HNPCC (biliary, small intestinal, urothelial, gallbladder, young-onse...

Familial sarcoma: challenging pedigrees.

Lynch(Henry T),Deters(Carolyn A),Hogg(Davi... Cancer 2003-11-05

...BRCA1 mutation, and p53 mutation in a Li-Fraumeni syndrome.,Sarcoma-prone families reported in the current study were se...

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