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Mutational profiling using liquid biopsy to guide targeted therapy in patients …

Mazouji(O),Ouhajjou(A),Anouar(N),Nejjari(C),… Sci Rep 2025-04-01

...NF1 were the most frequently mutated in our patients. Our study highlights the potential benefits of personalized medici...

Methodology, Criteria, and Characterization of Patient-Matched Thyroid Cell Lin…

Marlow(LA),Rohl(SD),Miller(JL),Knauf(JA),Fag… J Clin Endocrinol Metab 2018-00-01

...NF1, and EIF1AX). We established seven new thyroid cell lines (LAM136, EAM306, SDAR1, SDAR2, JEM493, THJ529, and THJ560)...

Resolving the phylogenetic origin of glioblastoma via multifocal genomic analys…

Brastianos(PK),Nayyar(N),Rosebrock(D),Leshch… NPJ Precis Oncol 2017-00-00

...NF1(n = 3), TP53(n = 4) and EGFR(n = 5). However, by phylogenetic analysis, there were no protein-coding mutations as re...

Neuropsychological profile in Italian children with neurofibromatosis type 1 (N…

Parmeggiani(A),Boiani(F),Capponi(S),Duca(M),… Eur J Paediatr Neurol 2018-09-00

Neurofibromatosis type 1 is a genetic disorder associated with cognitive deficits, learning disabilities and behavioral ...

Targeted delivery of resveratrol using PEGylated PLGA nanoparticles decorated w…

Tomar(S),Joshi(K),Chaudhary(V),Singh(R),Chau… Drug Dev Ind Pharm 2025-12-00

...NF1-NF8) were evaluated for particle size, zeta potential, drug loading, entrapment efficiency, and in vitro release. Su...

Extra-central nervous system metastasis from high-grade glioma: a single-instit…

Faraj(CA),McCutcheon(IE),Gubbiotti(MA),Perni… J Neurooncol 2025-05-00

...NF1, TERT promoter, and BRAF V600E mutations. Median OS from HGG diagnosis was 23.4 months, and median OS following ECM ...

Genomic characterization of patients with colorectal cancer.

Mahdouani(M),Zhuri(D),Dusenkalkan(F),Gurkan(… Hered Cancer Clin Pract 2025-09-26

...NF1, ABRAXAS1, ERBB2, FGFR, and CHEK2, necessitating further investigation to determine their potential role in CRC pred...

Targetable Alterations in Adult Patients With Soft-Tissue Sarcomas: Insights fo…

Lucchesi(C),Khalifa(E),Laizet(Y),Soubeyran(I… JAMA Oncol 2018-00-01

...NF1, CDKN2B, KMT2D, GLI1, ATM, TERT, PI3KCA, NOTCH1, MAP2K4, ERBB4, ARID1A, TSC2, and TNFAIP3. At least 1 targetable GA ...

Multi-gene panel sequencing reveals the relationship between driver gene mutati…

Li(J),Li(X),Guo(H),Zhou(S),Ding(H),Li(B),Li(… Discov Oncol 2025-03-07

...NF1 (p < 0.01), KRAS (p < 0.01), and TP53 (p < 0.001) were significantly associated with gender. This work revealed the ...

Analysis of Gene Expression Variance in Schizophrenia Using Structural Equation…

Igolkina(AA),Armoskus(C),Newman(JRB),Evgrafo… Front Mol Neurosci 2018-00-00

...NF1, and KRAS and SOS1 in the MAPK pathway; between PSPH and SHMT2 in serine biosynthesis; between AKT3 and TSC2 in the ...

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