...BRCA1/2 mutations and unclassified variant BRCA1/2 alterations. Forty cases of sporadic breast cancers were also investi...
...BRCA1/2 genes.,We convened an ovarian cancer symposium at the University of Pittsburgh in May 2002. Nineteen leading sci...
...BRCA1/2 genes, and their possible etiologic relationship with various forms of inherited cancer, has been recognized uni...
...BRCA1 mutation carriers, 136 BRCA2 carriers, and 1143 women without a known mutation (208 BRCA1/BRCA2 noncarriers and 93...
We analyzed the complete coding region with adjacent intron sequences of the BRCA1 gene in eight patients with hereditar...
...BRCA1 and NBS1. Damaged BS cells formed BRCA1/NBS1 foci with markedly delayed kinetics. Helicase-defective BLM showed do...
...BRCA1-binding region at the C terminus. In a BRCA1-dependent manner, ZBRK1 represses Gadd45a transcription through bindi...
...BRCA1 and BRCA2. It is believed that genes of lower penetrance, but of greater prevalence, may also modulate a woman's r...
...BRCA1-C terminal (BRCT) domain, a proline-rich region, helix-hairpin-helix (HhH) and pol X motifs. Since the amino acid ...
...BRCA1 CpG island is methylated, whereas this region is unmethylated in mature germ cells and early embryos. In gametes, ...
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