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Microsatellite instability in hereditary and sporadic breast cancers.

Adem(Camilo),Soderberg(Cheryl L),Cunningha... Int J Cancer 2003-11-20

...BRCA1/2 mutations and unclassified variant BRCA1/2 alterations. Forty cases of sporadic breast cancers were also investi...

Ovarian cancer and high-risk women-implications for prevention, screening, an...

Modugno(Francesmary), Gynecol Oncol 2003-10-30

...BRCA1/2 genes.,We convened an ovarian cancer symposium at the University of Pittsburgh in May 2002. Nineteen leading sci...

Psychosocial issues associated with genetic testing for breast and ovarian ca...

Pasacreta(Jeannie V) Cancer Invest 2003-10-23

...BRCA1/2 genes, and their possible etiologic relationship with various forms of inherited cancer, has been recognized uni...

Disruption of the expected positive correlation between breast tumor size and...

Foulkes(William D),Metcalfe(Kelly),Hanna(W... Cancer 2003-10-30

...BRCA1 mutation carriers, 136 BRCA2 carriers, and 1143 women without a known mutation (208 BRCA1/BRCA2 noncarriers and 93...

[Sequence analysis of BRCA1 gene in young breast cancer patients and/or posit...

Hampl(M),Plaschke(J),Burgemeister(R),Schwa... Langenbecks Arch Chir Suppl... 2003-11-03

We analyzed the complete coding region with adjacent intron sequences of the BRCA1 gene in eight patients with hereditar...

Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of ...

Davalos(Albert R),Campisi(Judith) J Cell Biol 2003-11-12

...BRCA1 and NBS1. Damaged BS cells formed BRCA1/NBS1 foci with markedly delayed kinetics. Helicase-defective BLM showed do...

Degradation of transcription repressor ZBRK1 through the ubiquitin-proteasome...

Yun(Jeanho),Lee(Wen-Hwa) Mol Cell Biol 2003-11-25

...BRCA1-binding region at the C terminus. In a BRCA1-dependent manner, ZBRK1 represses Gadd45a transcription through bindi...

Androgen receptor gene polymorphism and breast cancer susceptibility in The P...

Liede(Alexander),Zhang(William),De Leon Ma... Cancer Epidemiol Biomarkers... 2003-12-12

...BRCA1 and BRCA2. It is believed that genes of lower penetrance, but of greater prevalence, may also modulate a woman's r...

Over-expression of human DNA polymerase lambda in E. coli and characterizatio...

Shimazaki(Noriko),Yoshida(Kenta),Kobayashi... Genes Cells 2003-01-03

...BRCA1-C terminal (BRCT) domain, a proline-rich region, helix-hairpin-helix (HhH) and pol X motifs. Since the amino acid ...

Epigenetic marks at BRCA1 and p53 coding sequences in early human embryogenesis.

Magdinier(Frédérique),D'Estaing(Sandrine G... Mol Hum Reprod 2003-01-17

...BRCA1 CpG island is methylated, whereas this region is unmethylated in mature germ cells and early embryos. In gametes, ...

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