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TP53 BRCA1 CRISPR single-cell cancer

Baars(B),Orive-Ramos(A),Emmett(MJ),Gaire(B),… Mol Cancer Res 2026-01-02

...NF1 loss, showed low sensitivity. SHP2 plus MEK inhibition resulted in low selectivity, and RAS Q61X models were resista...

Urla(C),Fuchs(J),Grimm(A),Schmidt(A),Schäfer… J Cancer Res Clin Oncol 2023-07-00

...NF1 associated neurofibromas (10), neuroblastomas (5), desmoid tumors (2), MPNST (2), ganglioneuroma (1), Ewing sarcoma ...

Angeloni(LL),Jorente(J),Oliveira Sobrinho(RP… Einstein (Sao Paulo) None

...NF1 variants and two previously unreported double diagnoses.

Aydin(S),Kurtcan(S),Alkan(A),Guler(S),Filiz(… Clin Imaging 2016-00-00

...NF1.

Hsu(EJ),Thomas(J),Maher(EA),Youssef(M),Timme… Discov Oncol 2022-11-15

...NF1 mutations had worse OS (HR 1.990, p = 0.0540), while CDKN2A wild type patients had improved OS (HR 0.229, p = 0.0723...

Georgoulias(G),Zaravinos(A) Front Immunol 2022-00-00

...NF1 or RAS mutational status. Somatic mutations in IDO1 and HLA-DRA were frequent and could be involved in hindering pat...

Gerratana(L),Movarek(M),Wehbe(F),Katam(N),Ma… JCO Precis Oncol 2022-00-00

...NF1). Tumor mutational burden (TMB) varied significantly across tumor types, and patients with high MAF or NDA had a sig...

McCoach(CE),Le(AT),Gowan(K),Jones(K),Schuber… Clin Cancer Res 2018-00-15

...NF1 In addition, we identified CNV in multiple proto-oncogenes genes including PDGFRA, KIT, KDR, GNAS, K/HRAS, RET, NTRK...

Odhiambo(DA),Fan(S),Hirbe(AC) Cancers (Basel) 2025-01-07

...NF1), the five-year survival rate is at 20-50%, with recurrence occurring in up to 50% of individuals. For patients with...

Barnett(RM),Jang(A),Lanka(S),Fu(P),Bucheit(L… Commun Med (Lond) 2024-12-02

...NF1, BRCA2, ARID1A, and APC were the most frequently altered genes. In this study, the practice of offering an ICIs base...

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