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TP53 BRCA1 CRISPR single-cell cancer

Carvalho(Marcelo A),Billack(Blase),Chan(Em... Cancer Biol Ther 2003-08-15

...BRCA1 functions in DNA repair and transcriptional regulation. A major hurdle to dissect the role of BRCA1 is the lack of...

de la Hoya(M),Díez(O),Pérez-Segura(P),Godi... J Med Genet 2003-08-05

To test whether statistical models developed to calculate pre-test probability of being a BRCA1/2 carrier can differenti...

Nixon(R M),Duffy(S W) J Cancer Epidemiol Prev 2003-08-05

...BRCA1 or BRCA2 gene. These mutations confer a substantially increased risk of breast cancer. These are also published ra...

Wang(Peixiang),Branch(Donald R),Bali(Meena... Biochem J 2003-10-20

...BRCA1 (breast-cancer susceptibility gene 1), OCT3 does not repress human or mouse BRCA1/Brca-1 promoters. However, OCT3 ...

de Sanjosé(Silvia),Léoné(Mélanie),Bérez(Vi... Int J Cancer 2003-09-09

...BRCA1 and BRCA2 mutations. Nine of the 136 (6.6%) were found to carry BRCA deleterious mutations (MUT) (1 BRCA1 and 8 BR...

Berton(Thomas R),Matsumoto(Takashi),Page(A... Oncogene 2003-10-16

...Brca1 conditional knockout mice dramatically accelerated tumor development. In addition, Brca1 heterozygous female mice ...

Pignatelli(Miguel),Cocca(Claudia),Santos(A... Oncogene 2003-10-16

...BRCA1 gene expression and might therefore be important for the BRCA1 regulatory pathway involved in the pathogenesis of ...

Feng(Jinong),Yan(Jin),Chen(Jiesheng),Schla... Cancer Genet Cytogenet 2003-10-01

...BRCA1/BRCA2 genes in that germline mutations are important in cancer predisposition, but somatic mutations are seldom pr...

Powell(Simon N),Kachnic(Lisa A) Oncogene 2003-10-01

...BRCA1 and BRCA2, predisposes individuals to breast and ovarian cancers. Current progress in determining the function of ...

Krause(Darren R),Jonnalagadda(Jyoti C),Gat... Oncogene 2003-10-07

...BRCA1 are dispensable for TLK suppression. Overall, we propose that ATM activation is not linked solely to DSBs and that...

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