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Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro tra...

Krum(Susan A),Womack(James E),Lane(Timothy F) Oncogene 2003-10-07

...BRCA1-positive nuclear speckles in late S phase and G2/M phase cells. Bovine BRCA1 was phosphorylated and nuclear speckl...

Differential involvement of the hMRE11/hRAD50/NBS1 complex, BRCA1 and MLH1 in...

Habraken(Yvette),Jolois(Olivier),Piette(Ja... Oncogene 2003-10-07

...BRCA1 or MLH1 were analysed. NBS- and hMRE11-deficient cells present a classical kinetic of NF-kappaB induction after ca...

Twenty-three novel BRCA1 and BRCA2 sequence alterations in breast and/or ovar...

Meyer(Peter),Voigtlaender(Theda),Bartram(C... Hum Mutat 2003-10-27

...BRCA1 and 8 novel BRCA2 sequence variants. Predictions on the BRCA1/BRCA2 protein functions lead to the identification o...

Detection of the most frequent mutations in BRCA1 gene on polyacrylamide gels...

Janatová(M),Pohlreich(P),Matous(B) Neoplasma 2003-11-18

Heterozygous carriers of germ-line mutations in the BRCA1 gene are at high risk for the development of breast and ovaria...

Hereditary ovarian cancer in Poland.

Menkiszak(Janusz),Gronwald(Jacek),Górski(B... Int J Cancer 2003-11-17

...BRCA1 or BRCA2 genes. In Poland, 3 common founder mutations in BRCA1 account for the majority of families with identifie...

Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinuc...

Spiro(Craig),McMurray(Cynthia T) Mol Cell Biol 2003-09-24

...BRCA1 complexes but invokes repair by other pathways.

Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 a...

Du(Li-Lin),Nakamura(Toru M),Moser(Bettina ... Mol Cell Biol 2003-09-24

...BRCA1, has been suggested to act as an adapter protein facilitating the phosphorylation of specific substrates by Rad3-R...

Mutational analysis of the LMO4 gene, encoding a BRCA1-interacting protein, i...

Sutherland(Kate D),Visvader(Jane E),Choong... Int J Cancer 2003-10-09

...BRCA1 and that LMO4 can repress its transcriptional activity. Since proto-oncogene deregulation can result from activati...

Dhh1 regulates the G1/S-checkpoint following DNA damage or BRCA1 expression i...

Westmoreland(T J),Olson(J A),Saito(W Y),Hu... J Surg Res 2003-10-21

...BRCA1 in the yeast Saccharomyces cerevisiae is lethal. To identify potential new BRCA1-interacting gene targets, we char...

Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutati...

Modugno(Francesmary),Moslehi(Roxana),Ness(... Cancer Causes Control 2003-12-04

...BRCA1/2 carriers and non-carriers with ovarian cancer. However, the effects of tubal ligation may differ between BRCA1 c...

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