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TP53 BRCA1 CRISPR single-cell cancer

Mazouji(O),Ouhajjou(A),Anouar(N),Nejjari(C),… Sci Rep 2025-04-01

...NF1 were the most frequently mutated in our patients. Our study highlights the potential benefits of personalized medici...

Marlow(LA),Rohl(SD),Miller(JL),Knauf(JA),Fag… J Clin Endocrinol Metab 2018-00-01

...NF1, and EIF1AX). We established seven new thyroid cell lines (LAM136, EAM306, SDAR1, SDAR2, JEM493, THJ529, and THJ560)...

Tanabe(H),Ando(K),Takahashi(K),Kamanaka(T),Y… J Cancer Res Clin Oncol 2025-09-10

...NF1 were associated with worse OS. Interestingly, PTEN mutations were linked to improved survival. TP53 alterations were...

D'Amico(RS),Zanazzi(G),Wu(P),Canoll(P),Bruce… J Neurooncol 2018-10-00

...NF1. Adjuvant radiation and chemotherapy was employed in 87.5% and 75.0% of patients, respectively. Median overall survi...

Mahdouani(M),Zhuri(D),Dusenkalkan(F),Gurkan(… Hered Cancer Clin Pract 2025-09-26

...NF1, ABRAXAS1, ERBB2, FGFR, and CHEK2, necessitating further investigation to determine their potential role in CRC pred...

LiNa(S),Jianfei(T),Zhifeng(T),Xinbin(W),Hui(… Braz J Otorhinolaryngol 2025-00-00

...NF1 (22%), SMARCB1 (21%), TP53 (12%), SUZ12 (19%), and less commonly in BRAF and CDKN2A (each 2%). Radiotherapy improves...

Li(H),Sisoudiya(SD),Martin-Giacalone(BA),Kha… J Natl Cancer Inst 2021-07-01

...NF1). Notably, 5 patients had well-described oncogenic missense variants in HRAS (p.G12V and p.G12S) associated with Cos...

Awad(MM),Liu(S),Rybkin(II),Arbour(KC),Dilly(… N Engl J Med 2021-00-24

...NF1 and PTEN. In two of nine patients with lung adenocarcinoma for whom paired tissue-biopsy samples were available, his...

Ferreira(I),Droop(A),Edwards(O),Wong(K),Harl… Mod Pathol 2021-11-00

...NF1 mutations (5) in the conventional component, which was also detected in the corresponding de-/trans-differentiated c...

Kim(J),Light(N),Subasri(V),Young(EL),Wegman-… JCO Precis Oncol 2021-00-00

...NF1, DICER1, mismatch repair genes), rarely (BRCA2, CBL, CHEK2, SMARCA4), or never (FGFR4) reported in RMS. Numerous gen...

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