...BRCA1/2 mutations (gBRCA1/2m) and those with gBRCA1/2 wild-type (gBRCA1/2wt) using Kaplan-Meier estimates, the log-rank ...
...BRCA1/2 and ATM. HRD-positive tumours were more common among non-endometrioid histologies, high-grade disease, and poor-...
...BRCA1 gene within a concentration range of 100-1500 nM, with a detection limit of 270 nM. Both assays enabled quantitati...
...BRCA1 knockout models, and syngeneic mouse models. Techniques such as immunohistochemistry, multiplex immunofluorescence...
...BRCA1, ESR1, and BCL2 were located at the center of the PPI network, and BRCA1 was identified as the core regulatory tar...
...BRCA1, BRCA2, ATM, CHEK2, and TP53). Subgroup analyses were performed according to cohort type and ancestry. Univariable...
...BRCA1-associated protein-1 (BAP1) in the human hepatoma-derived cell line HepG2/8F_HS. A transient heat stimulus (43 °C,...
...BRCA1 or BRCA2, is associated with increased risks of breast, ovarian, pancreatic, and prostate cancers. Although long-t...
...BRCA1 (20%), and Lynch syndrome genes PMS2 (13%) and MSH6 (6%). Most variants were loss-of-function (78%) and inherited ...
BRCA1/2 germline pathogenic variants confer markedly elevated lifetime risks for breast, ovarian, prostate, and pancreat...
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