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Familial invasive and borderline ovarian tumors by proband status, age and hi...

Hemminki(Kari),Granström(Charlotta) Int J Cancer 2003-07-17

...BRCA1/2 mutation analysis and relative risks of ovarian and breast cancer suggests that these mutations could account fo...

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-li...

Brzovic(Peter S),Keeffe(Jennifer R),Nishik... Proc Natl Acad Sci U S A 2003-07-01

...BRCA1BARD1 RING complex functions as an ubiquitin (Ub) ligase with activity substantially greater than individual BRCA1 ...

Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in ...

Zhou(Chenyi),Smith(Janice L),Liu(Jinsong) Oncogene 2003-05-23

...BRCA1. Our results suggest that the deletion of the C-terminal 49 amino acids of BRCA1 results in a loss of BRCA1 functi...

Breast cancer risk reduction associated with the RAD51 polymorphism among car...

Jakubowska(Anna),Narod(Steven A),Goldgar(D... Cancer Epidemiol Biomarkers... 2003-09-12

The observed heterogeneity of breast cancer risk among women who carry the same BRCA1 mutation suggests the existence of...

Loss of coordinated androgen regulation in nonmalignant ovarian epithelial ce...

Evangelou(Andreas),Letarte(Michelle),Juris... Cancer Res 2003-06-23

...BRCA1 or 2 mutation (n = 9), and from the ascitic fluid of patients with primary ovarian cancer (n = 8) were cultured wi...

Breast cancer risk associated with genotypic polymorphism of the nonhomologou...

Fu(Yi-Ping),Yu(Jyh-Cherng),Cheng(Ting-Chih... Cancer Res 2003-06-23

...BRCA1 and BRCA2, in the homologous recombination pathway for DNA double-strand break (DSB) repair suggests that the mech...

Regulation of BRCA1 transcription by specific single-stranded DNA binding fac...

Thakur(Sanjay),Nakamura(Tatsuya),Calin(Geo... Mol Cell Biol 2003-07-03

...BRCA1 mRNA, we investigated the factors regulating BRCA1 transcription. Factors with specific affinity for the previousl...

Assembly of functional ALT-associated promyelocytic leukemia bodies requires ...

Wu(Guikai),Jiang(Xianzhi),Lee(Wen-Hwa),Che... Cancer Res 2003-06-23

...BRCA1 COOH-terminal domain, is required for this activity. Although TRF1 interacts with NBS1 directly, it is dispensable...

[Characteristics of selected features of hereditary ovarian cancer in carrier...

Menkiszak(Janusz),Górski(Bohdan),Jakubowsk... Ginekol Pol 2003-06-02

Hereditary ovarian cancer in BRCA1 constitutional mutation carriers shows a characteristic clinical pattern.,Evaluation ...

Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors.

Krop(Ian),Maguire(Paula),Lahti-Domenici(Ja... Cancer Res 2003-06-16

...BRCA1 tumors and thought to harbor a BRCA1 modifier gene. To establish whether germ-line mutations in HIN-1 may influenc...

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