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TP53 BRCA1 CRISPR single-cell cancer

Taucher(Susanne),Gnant(Michael),Jakesz(Rai... Langenbecks Arch Surg 2003-09-16

The availability of genetic testing for inherited mutations in the BRCA1 and BRCA2 gene provides potentially valuable in...

Yossepowitch(Orit),Olvera(Narciso),Satagop... Leuk Lymphoma 2003-10-02

Mutations in the BRCA1 and BRCA2 tumor suppressor genes are associated with an increased risk for breast and ovarian can...

McEachern(Kristen A),Archey(William B),Dou... J Cell Biochem 2003-10-30

...BRCA1(L) and BRCA1(S) was also investigated. Mutant BRCA1 retained wild type levels of transcriptional activity for the ...

Fan(Wen-Hong),Zhan(Qi-Min) Ai Zheng 2003-09-12

BRCA1 is a 220kDa nuclear protein with multiple functional domains. It interacts directly or indirectly with a variety o...

Gong(Gail),Whittemore(Alice S) Genet Epidemiol 2003-07-23

...BRCA1/2 genes. We studied the effects of risk heterogeneity due to unmeasured, shared risk factors by including risk var...

Bernard-Gallon(Dominique J),Déchelotte(Pie... Anticancer Res 2003-04-17

...BRCA1 and BRCA2 genes. It seems that altered expressions of BRCA1 and BRCA2 genes may contribute to breast cancer develo...

Bellino(Roberto),Arisio(Riccardo),D'Addato... Anticancer Res 2003-04-17

...BRCA1 mutation similar to the one responsible for sickle cell disease, possibly altering the spatial structure of the ge...

Antoniou(A),Pharoah(P D P),Narod(S),Risch(... Am J Hum Genet 2003-07-01

Germline mutations in BRCA1 and BRCA2 confer high risks of breast and ovarian cancer, but the average magnitude of these...

Taniguchi(Toshiyasu),Tischkowitz(Marc),Ame... Nat Med 2003-06-26

...BRCA1 and BRCA2 (FANCD1). Here we show that the FANC-BRCA pathway is disrupted in a subset of ovarian tumor lines. Mono-...

Hutson(Sadie Pauline) Oncol Nurs Forum 2003-09-16

...BRCA1 and BRCA2, researchers have studied some of the initial psychosocial effects of genetic information on women at hi...

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