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The Fanconi anaemia/BRCA pathway.

D'Andrea(Alan D),Grompe(Markus) Nat Rev Cancer 2003-02-10

...BRCA1, ATM and NBS1. The FA proteins could therefore be involved in the cell-cycle checkpoint and DNA-repair pathways. R...

[Report on the first year of the activity of the National Oncological RD Cons...

Tímár(József) Magy Onkol 2003-03-26

...BRCA1 mutation patterns of familiar breast cancer and DNA repair enzyme polymorphism in head and neck cancer. New method...

Amplification of HSD17B1 and ERBB2 in primary breast cancer.

Gunnarsson(Cecilia),Ahnström(Marie),Kirsch... Oncogene 2003-01-30

...BRCA1. The aim of this study was to investigate if HSD17B1 shows an altered gene copy number in breast cancer. We used r...

Role of BRCA1 in heat shock response.

Xian Ma(Yong),Fan(Saijun),Xiong(Jingbo),Yu... Oncogene 2003-01-30

...BRCA1 (wtBRCA1). In addition to heat regulation of BRCA1 protein levels, we also found that BRCA1 could modulate the hea...

Interaction between BRCA2 and replication protein A is compromised by a cance...

Wong(Johnson M S),Ionescu(Daniela),Ingles(... Oncogene 2003-01-30

...BRCA1 and BRCA2 genes predispose women to familial, early-onset breast cancer. Both the BRCA1 and BRCA2 proteins appear ...

Ovarian cancer associated with inherited mutations in BRCA1 or BRCA2.

Swisher(Elizabeth) Curr Womens Health Rep 2003-06-02

...BRCA1 or BRCA2 mutations. Women with BRCA1-associated ovarian cancers seem to have a somewhat better survival than women...

CSE1L/CAS: its role in proliferation and apoptosis.

Behrens(P),Brinkmann(U),Wellmann(A) Apoptosis 2003-07-31

...BRCA1. Inhibition of MEK1 mediated phosphorylation has been shown to enhance paclitaxel (Taxol) induced apoptosis in bre...

Role played by BRCA1 in regulating the cellular response to stress.

Gilmore(P M),Quinn(J E),Mullan(P B),Andrew... Biochem Soc Trans 2003-11-10

...BRCA1 in mediating the cellular response to stress. We review the role played by BRCA1 in detecting and signalling the p...

X-chromosome inactivation: X marks the spot for BRCA1.

Stone(Caroline),McCabe(Nuala),Ashworth(Ala... Curr Biol 2003-09-24

...BRCA1 breast cancer susceptibility gene has an important function in this epigenetic phenomenon.

Risk factors and risk reduction of breast and ovarian cancer.

Brekelmans(Cecile T M) Curr Opin Obstet Gynecol 2003-05-15

...BRCA1 or BRCA2 gene mutation, prophylactic surgery can significantly reduce the risk of breast as well as ovarian cancer...

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