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TP53 BRCA1 CRISPR single-cell cancer

Jang(SY),Kwon(M),Lee(J),Kim(ST) Cancers (Basel) 2026-08-26

...NF1-altered (n = 7, 6.5%), and quadruple-wild-type (n = 52, 48.1%). TMB-high status (10.2%) showed no significant associ...

Nannini(Margherita),Astolfi(Annalisa),Urbini… BMC Cancer 2015-05-28

...NF1), BRAF, or KRAS genes (RAS-pathway or RAS-P).In this extremely heterogeneous landscape, the clinical profile and mol...

Yao(ZG),Li(XL),Wen(WJ),Lin(XY),Zhang(GH),Sun… Acta Neuropathol Commun 2026-03-05

...NF1 (64.3%, 18/28), along with activating mutations in PDGFRA (39.3%, 11/28) and EGFR (32.1%, 9/29), suggesting tumor pr...

Yatawara(L),Hewavithana(B),Ramanayake(AP),Wi… Breast Cancer (Auckl) None

...NF1 [c.288+41G>A; c.328+37C>G;]. Pathogenic variants occurred in fewer than 10% of individuals in any group, and other v...

Leng(H),Song(ZX),Liu(Y),Wang(YX),Yang(J),Hu(… Zhonghua Bing Li Xue Za Zhi 2026-03-08

...NF1, SMARCA4, and RET (P<0.05). Transcriptomic analysis demonstrated upregulation of immune-related genes (CCL21, CXCL2)...

Gao(H),Wang(H),Yao(L),Zhao(G),Tang(L),Zhang(… Front Biosci (Landmark Ed) 2026-03-26

...NF1 and supported lineage continuity from P2 to P50 through shared SNVs and conserved driver events. CD133+ SHG142 GSCs ...

Fagbohun(OF),Oladipo(AO),Gao(C),Olawoye(B),B… Cell Death Discov 2026-04-10

...NF1, and CHEK2) and deciphered the functional consequences leveraging the higher throughput Illumina NovaSeq X and NextS...

Yeung(MCF),Lefkowitz(RA),Antonescu(CR) Mod Pathol 2026-05-00

...NF1, NF2, SMARCB1, and LZTR1 or chromosome 22q loss. Patients had stable disease with no significant radiologic progress...

Martinez-Enriquez(LC),Bernal-Estévez(DA),Alz… Front Oncol None

...NF1 (p.Phe1593SerfsTer31), and PIK3CA (p.Glu542Lys), all supported by OncoKB level-1 evidence. This case highlights the ...

Adamson(AW),Ding(YC),Steele(L),Leong(LA),Mor… Res Sq 2023-02-20

...NF1 . In total, 38% (27/71) of HGSC patients harbored pathogenic variants in DNA homologous recombination repair genes. ...

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