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TP53 BRCA1 CRISPR single-cell cancer

Montagna(Marco),Dalla Palma(Maurizia),Meni... Hum Mol Genet 2003-12-18

...BRCA1 mutation, and 15 were previously shown to carry a mutation in either the BRCA2 (five families) or BRCA1 gene (10 f...

Liu(Kang),Lin(Fang-Tsyr),Ruppert(J Michael... Mol Cell Biol 2003-05-29

...BRCA1 carboxyl-terminal) motifs and upon DNA damage is recruited to stalled replication forks, where it participates in ...

Benezra(Miriam),Chevallier(Nathalie),Morri... J Biol Chem 2003-08-27

BRCA1 is a tumor suppressor gene mutated in cases of hereditary breast and ovarian cancer. BRCA1 protein is involved in ...

Ye(Qi-Nong),Hu(Yan-Fen),Zhong(Hong-Jun),Li... Sheng Wu Gong Cheng Xue Bao 2003-07-10

...BRCA1) plays an important role in breast cancer development and progression. BRCA1 encodes a 1863-amino acid protein wit...

Fedier(André),Steiner(Rolf A),Schwarz(Viol... Int J Oncol 2003-08-11

...Brca1 function. We report that Brca1-deficiency in p53-null cells was associated with increased sensitivity to the topoi...

Taniguchi(Toshiyasu),Tischkowitz(Marc),Ame... Nat Med 2003-06-26

...BRCA1 and BRCA2 (FANCD1). Here we show that the FANC-BRCA pathway is disrupted in a subset of ovarian tumor lines. Mono-...

Hutson(Sadie Pauline) Oncol Nurs Forum 2003-09-16

...BRCA1 and BRCA2, researchers have studied some of the initial psychosocial effects of genetic information on women at hi...

Wojciechowska-Lacka(A),Markowska(J),Skasko... Eur J Gynaecol Oncol 2003-07-22

...BRCA1 mutation, and in 35 patients with Stage III sporadic ovarian tumors.,Progressive disease within first six months f...

DiGianni(Lisa M),Kim(Haesook T),Emmons(Kar... Cancer Epidemiol Biomarkers... 2003-09-26

...BRCA1/2 testing program. CAM use and correlates of use were assessed using logistic regression models. CAM was used by 5...

Taucher(Susanne),Gnant(Michael),Jakesz(Rai... Langenbecks Arch Surg 2003-09-16

The availability of genetic testing for inherited mutations in the BRCA1 and BRCA2 gene provides potentially valuable in...

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