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TP53 BRCA1 CRISPR single-cell cancer

Leng(H),Song(ZX),Liu(Y),Wang(YX),Yang(J),Hu(… Zhonghua Bing Li Xue Za Zhi 2026-03-08

...NF1, SMARCA4, and RET (P<0.05). Transcriptomic analysis demonstrated upregulation of immune-related genes (CCL21, CXCL2)...

Jang(SY),Kwon(M),Lee(J),Kim(ST) Cancers (Basel) 2026-08-26

...NF1-altered (n = 7, 6.5%), and quadruple-wild-type (n = 52, 48.1%). TMB-high status (10.2%) showed no significant associ...

Ross(Jeffrey S),Wang(Kai),Gay(Laurie),Otto(G… JAMA Oncol 2016-04-01

...NF1, NF2, NRAS, RAF1, RET, and ROS1 were found in 90 (72%) ACUPs but in only 29 (39%) non-ACUPs (P < .001).,Almost all C...

Yu(Yadong),Lü(Xiaoying),Ding(Fei) J Neural Eng 2016-04-11

...Nf1 gene and thereby, affect cytoskeleton regulation and MAPK pathway; (2) miR-92a, miR-339-5p, miR-25, miR-125a-5p, miR...

Huang(R),Shen(G),Ren(Y),Zheng(K),Wang(J),Shi… J Transl Med 2023-00-04

...NF1 (10.8%), APC (7.2%), and ARID2 (6%). Copy number variations (CNV) were commonly found in CCND1 (19.3%), CDK4 (19.3%)...

Adamson(AW),Ding(YC),Steele(L),Leong(LA),Mor… Res Sq 2023-02-20

...NF1 . In total, 38% (27/71) of HGSC patients harbored pathogenic variants in DNA homologous recombination repair genes. ...

Shi(K),Wang(B),Dou(L),Wang(S),Fu(X),Yu(H) Front Physiol 2022-00-00

...NF1 family TF motifs (NFIA, NFIB, NFIC, and NFIX), GRE, Fox:Ebox, PGR, and ARE. Among these, Nfib and Nfix exhibited abn...

Li(X),Cen(M),Xu(J),Zhang(H),Xu(XS) J Pathol Inform 2022-00-00

...NF1, and FAT1) in LUAD. We proved the concept that fine-tuning the pretrained ImageNet neural networks with histopatholo...

Gupta(K),Jones(JC),Farias(VA),Mackeyev(Y),Si… Front Oncol 2022-00-00

...NF1 make GBMs have an intrinsically high KRAS activity. We show the combination of nilotinib plus lapatinib to exhibit m...

Moran(JMT),Le(LP),Nardi(V),Golas(J),Farahani… Mod Pathol 2022-00-00

...NF1-mutant tumors and were detected in 5.6% of triple wild-type melanomas. Interestingly, gene rearrangements were signi...

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