Mutations in the BRCA1 and BRCA2 tumor suppressor genes are associated with an increased risk for breast and ovarian can...
...BRCA1(L) and BRCA1(S) was also investigated. Mutant BRCA1 retained wild type levels of transcriptional activity for the ...
...BRCA1 and BRCA2 genes. It seems that altered expressions of BRCA1 and BRCA2 genes may contribute to breast cancer develo...
...BRCA1 mutation similar to the one responsible for sickle cell disease, possibly altering the spatial structure of the ge...
Germline mutations in BRCA1 and BRCA2 confer high risks of breast and ovarian cancer, but the average magnitude of these...
...BRCA1 gene are associated with more than half the cases of hereditary breast cancer. Breast cancer formation in BRCA1 mu...
...BRCA1 or BRCA2 mutation.,We examined prospectively the use of BRCA1/BRCA2 testing in all women with a primary breast or ...
Hereditary ovarian cancer in BRCA1 constitutional mutation carriers shows a characteristic clinical pattern.,Evaluation ...
...BRCA1 and BRCA2 genes have been of great interest, these genes account for less than 5% of all breast carcinoma cases. T...
...BRCA1 mutations and 12 BRCA2 mutations. BRCA heterozygotes were younger compared with Jewish patients who had EOC withou...
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