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BRCA1 testing and informed consent in a woman with mild retardation.

Schneider(K A),Kieffer(S A),Patenaude(A F) J Genet Couns 2003-02-11

...BRCA1 testing to a woman with limited intellectual capacity and documented psychological distress. This case is one of s...

Prophylactic surgery and other strategies for reducing the risk of familial o...

Swisher(Elizabeth) Curr Treat Options Oncol 2003-07-07

...BRCA1 and BRCA2 mutations are diagnosed with occult cancer at the time of surgical prophylaxis. Surgical prophylaxis sho...

Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining gen...

Morales(Julio C),Xia(Zhenfang),Lu(Tao),Ald... J Biol Chem 2003-07-16

...BRCA1 tumor suppressor, and knock-down experiments with small interfering RNA have revealed a role for the protein in th...

Mutations of BRCA genes in hereditary breast and ovarian cancer.

Radice(P) J Exp Clin Cancer Res 2003-07-31

BRCA1 and BRCA2 are the main genetic elements associated with hereditary susceptibility to breast and ovarian cancer tha...

Hereditary risk of breast cancer: not only BRCA.

Turchetti(D),Cortesi(L),Federico(M),Romagn... J Exp Clin Cancer Res 2003-07-31

The BRCA1 and BRCA2 genes are involved in genetic susceptibility to breast cancer (BC). Nevertheless, in a relevant numb...

Evaluating breast cancer risk: available models to assess individual breast c...

Pasini(B),Casalis Cavalchini(G C),Genovese... J Exp Clin Cancer Res 2003-07-31

...BRCA1 or BRCA2 germ line mutation. Each model, based on a slightly different study design and purpose, takes into accoun...

Perspectives in the clinical management of BRCA mutations carriers.

Savarese(A),Cognetti(F) J Exp Clin Cancer Res 2003-07-31

...BRCA1 and BRCA2 is changing the clinical care provided to women at high-risk of breast cancer. We briefly review what is...

The Italian multi-centre project on evaluation of MRI and other imaging modal...

Podo(F),Sardanelli(F),Canese(R),D'Agnolo(G... J Exp Clin Cancer Res 2003-07-31

...BRCA1 or BRCA2 mutation carriers or had a 1 in 2 probability of being carriers (40/105 with a previous personal history ...

Usefulness of breast MRI in a patient with genetic risk.

Cortesi(L),Canossi(B),De Santis(M),Panizza... J Exp Clin Cancer Res 2003-07-31

We describe an interesting case-report represented by a patient carrying BRCA1 mutation, recruited for the study "Multic...

Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse ma...

Kumaraswamy(Easwari),Carlson(Bradley A),Mo... Mol Cell Biol 2003-04-04

...BRCA1 and p53 was also altered in a contrasting manner in MMTV-Cre mice, suggesting greater susceptibility to cancer and...

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