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Hill(N),AlMuallim(HYO),Maddock(E),Hobbs(C)... FEBS Open Bio 2026-07-08

...BRCA1, while also attenuating neuroinflammatory activation. In addition, KCL-286 normalises microglial and astrocytic mo...

Chitphuk(S),Stitchantrakul(W),Wikiniyadhan... Comput Struct Biotechnol J None

...BRCA1-deficient cells. Crucially, the pipeline correctly classified ZINC67913374 as biologically inactive [median inhibi...

Wang(K),Geng(S),Xiao(Z),Jiang(H),Jiang(H) Mol Cell Biochem 2026-08-00

...BRCA1 and RAD51, and upregulates glycolytic regulators LDHA and HK2, thereby augmenting DNA damage repair capacity and g...

Betella(I),Fumagalli(D),Rappa(A),Sala(I),C... Int J Gynecol Cancer 2026-08-00

...BRCA1/2 mutation testing using SOPHiA DDM Homologous Recombination Deficiency Solution. Functional homologous recombinat...

Paixão(D),Barth(AL),Kiss(A),Monteleone(VF)... Sci Rep 2026-07-08

...BRCA1/2, CHEK2, TP53, ATM, and PALB2. Structural variants accounted for 7.6% of all P/LP findings and were predominantly...

Sjoquist(KM),Dobrovic(A),Robledo(KP),Nesic... Br J Cancer 2026-07-08

...BRCA1 (meBRCA1) or RAD51C (meRAD51C) or mutation of non-BRCA HR genes. This trial evaluated olaparib in platinum-sensiti...

Zhang(M),Niu(L),Lyu(H),Liu(Z),Zeng(H),Lu(Z... Chin Med J (Engl) 2026-07-07

...BRCA1/2. Based on dose-limiting toxicities and preliminary efficacy, daily famitinib 10 mg combined with dalpiciclib 100...

Omari(SK) Health Sci Rep 2026-07-00

...BRCA1/2, CHEK2, PALB2 are relatively prevalent among affected men, yet genetic counseling and cascade testing remain und...

Kruczkowska(KK),Gąsiorek(N),Wiraszka(R) Chin Clin Oncol 2026-06-00

The coexistence of a germline BRCA1 mutation and human epidermal growth factor receptor 2 (HER2)-positive breast cancer ...

Taris(N),Amand(NDS),Hild(C),Mathelin(C),Ch... Cancer Genet 2026-07-06

...BRCA1/2 genes to extensive multigene panels. Longitudinal data describing this transition in men remain scarce. All men ...