...BRCA1 or BRCA2 germ line mutation. Each model, based on a slightly different study design and purpose, takes into accoun...
...BRCA1 and BRCA2 is changing the clinical care provided to women at high-risk of breast cancer. We briefly review what is...
...BRCA1 or BRCA2 mutation carriers or had a 1 in 2 probability of being carriers (40/105 with a previous personal history ...
We describe an interesting case-report represented by a patient carrying BRCA1 mutation, recruited for the study "Multic...
...BRCA1 tumor suppressor, and knock-down experiments with small interfering RNA have revealed a role for the protein in th...
...BrCA1, BrCA2, and p53 genes.,A point mutation of the BrCA1 gene appears to inhibit soluble HLA secretion.,Among the thre...
...BRCA1 carboxy-terminus prevents normal BRCA1 function, such as BRCA1 association with nuclear foci following DNA damage....
Hereditary predisposition to breast and ovarian cancer, most commonly due to germline mutations in BRCA1 and BRCA2, has ...
...BRCA1 and BRCA2 mutations are diagnosed with occult cancer at the time of surgical prophylaxis. Surgical prophylaxis sho...
...BRCA1 and p53 was also altered in a contrasting manner in MMTV-Cre mice, suggesting greater susceptibility to cancer and...
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