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Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer.

Foulkes(William D),Stefansson(Ingunn M),Ch... J Natl Cancer Inst 2003-10-10

...BRCA1 mutation carriers (i.e., BRCA1-related breast cancers). We tested the hypothesis that BRCA1-related breast cancers...

Microsatellite instability in hereditary and sporadic breast cancers.

Adem(Camilo),Soderberg(Cheryl L),Cunningha... Int J Cancer 2003-11-20

...BRCA1/2 mutations and unclassified variant BRCA1/2 alterations. Forty cases of sporadic breast cancers were also investi...

The Norwegian founder mutations in BRCA1: high penetrance confirmed in an inc...

Heimdal(K),Maehle(L),Apold(J),Pedersen(J C... Eur J Cancer 2003-12-04

...BRCA1 (816delGT, 1135insA, 1675delA and 3347delAG) with regard to breast and ovarian cancers in families ascertained thr...

[Sequence analysis of BRCA1 gene in young breast cancer patients and/or posit...

Hampl(M),Plaschke(J),Burgemeister(R),Schwa... Langenbecks Arch Chir Suppl... 2003-11-03

We analyzed the complete coding region with adjacent intron sequences of the BRCA1 gene in eight patients with hereditar...

BRCT repeats as phosphopeptide-binding modules involved in protein targeting.

Manke(Isaac A),Lowery(Drew M),Nguyen(Anhco... Science 2003-11-10

...BRCA1 carboxyl-terminal) domains in PTIP (Pax transactivation domain-interacting protein) and in BRCA1 as phosphoserine-...

The BRCT domain is a phospho-protein binding domain.

Yu(Xiaochun),Chini(Claudia Christiano Silv... Science 2003-11-10

...BRCA1 BRCT domain directly interacts with phosphorylated BRCA1-Associated Carboxyl-terminal Helicase (BACH1). This speci...

Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2...

King(Mary-Claire),Marks(Joan H),Mandell(Je... Science 2003-11-10

...BRCA1 and BRCA2. We selected 1008 index cases, regardless of family history of cancer, and carried out molecular analysi...

Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of ...

Davalos(Albert R),Campisi(Judith) J Cell Biol 2003-11-12

...BRCA1 and NBS1. Damaged BS cells formed BRCA1/NBS1 foci with markedly delayed kinetics. Helicase-defective BLM showed do...

Degradation of transcription repressor ZBRK1 through the ubiquitin-proteasome...

Yun(Jeanho),Lee(Wen-Hwa) Mol Cell Biol 2003-11-25

...BRCA1-binding region at the C terminus. In a BRCA1-dependent manner, ZBRK1 represses Gadd45a transcription through bindi...

A biochemical analysis demonstrates that the BRCA1 intronic variant IVS10-2A-...

Keaton(Jessica C),Nielsen(David R),Hendric... J Hum Genet 2003-11-04

...BRCA1 IVS10-2A-->C revealed that functional BRCA1 mRNA was derived from only one of the patient's chromosomes. The other...

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