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Breast cancer risk associated with genotypic polymorphism of the nonhomologou...

Fu(Yi-Ping),Yu(Jyh-Cherng),Cheng(Ting-Chih... Cancer Res 2003-06-23

...BRCA1 and BRCA2, in the homologous recombination pathway for DNA double-strand break (DSB) repair suggests that the mech...

Assembly of functional ALT-associated promyelocytic leukemia bodies requires ...

Wu(Guikai),Jiang(Xianzhi),Lee(Wen-Hwa),Che... Cancer Res 2003-06-23

...BRCA1 COOH-terminal domain, is required for this activity. Although TRF1 interacts with NBS1 directly, it is dispensable...

Differentiating pathogenic mutations from polymorphic alterations in the spli...

Claes(Kathleen),Poppe(Bruce),Machackova(Ev... Genes Chromosomes Cancer 2003-07-28

About 4% of all BRCA1 and BRCA2 alterations reported to the Breast Information Core database are splice site variants. O...

Production of knockout rats using ENU mutagenesis and a yeast-based screening...

Zan(Yunhong),Haag(Jill D),Chen(Kai-Shun),S... Nat Biotechnol 2003-08-15

...Brca1 and Brca2 using a yeast gap-repair, ADE2-reporter truncation assay. We produced knockout rats for each of these tw...

Prognostic significance of BRCA1 expression in sporadic breast carcinomas.

Lambie(H),Miremadi(A),Pinder(S E),Bell(J A... J Pathol 2003-07-18

...BRCA1 protein expression in 100 breast cancers. BRCA1 expression was compared with known prognostic factors and survival...

Glomeruloid microvascular proliferation is associated with p53 expression, ge...

Goffin(J R),Straume(O),Chappuis(P O),Brune... Br J Cancer 2003-10-17

...BRCA1 germline mutations. The presence of GMP may influence treatment decisions.

A mutation analysis of the BRCA1 gene in 140 families from southeast France w...

Rostagno(Philippe),Gioanni(Jeanine),Garino... J Hum Genet 2003-10-06

...BRCA1 protein by modifying cysteine ligands from the RING finger domain. As expected BRCA1 gene alteration, including mi...

BRCA1 and BRCA2 genetic testing for ovarian cancer: is it all good news?

Balmer(Claire E) Eur J Oncol Nurs 2003-12-01

...BRCA1 and BRCA2 cancer susceptibility genes (Antoniou et al. 2000, Berchuk et al. 1999). This article will examine curre...

Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell l...

Fustier(P),Le Corre(L),Chalabi(N),Vissac-S... Br J Cancer 2003-08-05

...BRCA1 and BRCA2. We investigated the effects of resveratrol on BRCA1 and BRCA2 expression in human breast cancer cell li...

Repeated observation of breast tumor subtypes in independent gene expression ...

Sorlie(Therese),Tibshirani(Robert),Parker(... Proc Natl Acad Sci U S A 2003-09-04

...BRCA1 carriers in the analysis, we found that this genotype predisposes to the basal tumor subtype. Our results strongly...

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