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Routine germline genetic testing in 3552 unselected NHS breast cancer patient...

Torr(B),Mansour(L),Fierheller(CT),Hamill(M... NPJ Breast Cancer 2026-07-09

...BRCA1/BRCA2/PALB2) and 18.2% of gPVs in intermediate penetrance-BCSGs (CHEK2/ATM/RAD51C/RAD51D). Designing 'Ultra-simple...

Immunohistochemical and molecular diagnostics tailoring personalised ovarian ...

Kowalewski(AM),Szylberg(Ł) Pol J Pathol 2026-06-25

...BRCA1/2, homologous recombination deficiency (HRD) status, and circulating tumour DNA (ctDNA) monitoring. These diagnost...

RMI2 knockdown suppresses ovarian cancer cell growth by impairing DNA damage ...

Zhu(K),Li(Z),Wei(Y),Lin(Y) In Vitro Cell Dev Biol Anim 2026-07-10

...BRCA1, NBS1, RAD51). Under DNA damage stress induced by Olaparib, a Poly (ADP-ribose) Polymerase (PARP) inhibitor, RMI2 ...

TRDMT1-mediated mRNA m5C methylation decreases chemotherapy sensitivity by ac...

Luo(W),Chen(H),Fu(Y),Ye(L),Fu(B),Wang(J),Q... Cancer Lett 2026-07-10

...BRCA1, RAD51, and RAD52. Analysis of mRNA m5C modification sequencing in TRDMT1-deficient PDAC cells demonstrated that I...

Real-world clinical outcomes, genetic testing patterns, and treatment pattern...

George(DJ),Kariburyo-Yay(F),Aggarwal(H),Te... Urol Oncol 2026-09-00

...BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCL, PALB2, RAD51B, RAD51C, RAD51D, and RAD54L. Biomarker testing patterns a...

Stress-induced CD55 supports homologous recombination capacity and drives oxa...

Wang(T),Zhang(X),Yan(X),Wang(G),Zhao(L) Cell Commun Signal 2026-07-10

...BRCA1 induction, and prolonged γ-H2AX accumulation. In oxaliplatin-resistant cells, CD55 depletion converted the antagon...

Identification of FOXK1 and SEMA7A as key genes associated with m6A-related p...

Yang(J),Wu(Z),Dong(N) Hereditas 2026-07-10

...BRCA1-FOXK1-mmu-miR-7234-3p). Molecular docking showed that decitabine and other drugs bound well to FOXK1,warranting fu...

Examining the connection between BRCA1/2 mutations and uterine cancer: a comp...

Saleem(SM),Nasir(SAS),Nida(F),Khalid(M),Ga... Ann Med Surg (Lond) 2026-07-00

...BRCA1 folk and just 1 or 2% for BRCA2 folk. Yet, BRCA1 faults might bring worse sorts of womb growth. These have bad cel...

ZNF184 negatively regulates HR repair and predicts poor prognosis in acute ly...

Hwang(WC),Ju(HY),Park(K),Kwon(EJ),Seo(ES),... Nucleic Acids Res 2026-05-20

...BRCA1 recruitment, leading to accumulation of DNA damage. ZNF184 expression was elevated in primary ALL samples and asso...

The impact of breast cancer polygenic risk score disclosure on decisional con...

Ongaro(G),Salafia(C),Sheikh(R),Schofield(E... Genet Med 2026-08-00

...BRCA1/2 PVs and whether PRS magnitude interacts with individual characteristics. Unaffected women with BRCA1/2 PVs (N = ...

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