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TP53 BRCA1 CRISPR single-cell cancer

Lalloo(Fiona),Varley(Jennifer),Ellis(David... Lancet 2003-04-24

We aimed to assess frequency and penetrance of BRCA1, BRCA2,and TP53 mutations in women diagnosed with breast cancer age...

Hallowell(N),Foster(C),Eeles(R),Ardern-Jon... J Med Ethics 2003-06-06

...BRCA1/2 mutation searching-this paper describes how women, previously diagnosed with breast/ovarian cancer, perceive the...

Hogervorst(Frans B L),Nederlof(Petra M),Gi... Cancer Res 2003-04-22

...BRCA1 mutation-positive families. The MLPA test for BRCA1 ensures a sensitive and comprehensive high-throughput screenin...

Claus(Elizabeth B),Stowe(Meredith),Carter(... Breast Cancer Res Treat 2003-09-16

...BRCA1 and BRCA2, in the development of BCIS is unclear.,To better define the role of: (1) a family history of breast and...

Egawa(Chiyomi),Motomura(Kazuyoshi),Miyoshi... Breast Cancer Res Treat 2003-09-16

...BRCA1 mRNA levels high and low group according to the cut-off value of 0.55. Response rate (65%) of tumors with high BRC...

Trenz(Kristina),Landgraf(Julia),Speit(Günter) Breast Cancer Res Treat 2003-09-16

...BRCA1 mutation do not generally show the same mutagen sensitivity as lymphocytes with the same BRCA1 mutation. Therefore...

Lou(Zhenkun),Chini(Claudia Christiano Silv... J Biol Chem 2003-05-22

BRCA1 is a tumor suppressor involved in DNA repair and damage-induced checkpoint controls. In response to DNA damage, BR...

Olsson(Håkan L),Ingvar(Christian),Bladströ... Cancer 2003-04-02

...BRCA1 mutation carrier.

Fraga(Mario F),Ballestar(Esteban),Montoya(... Nucleic Acids Res 2003-03-28

...BRCA1, MLH1, GSTP1 and p16(INK4a) genes, and binding affinities for each case were calculated by Scatchard analyses. Wit...

Fedier(André),Steiner(Rolf A),Schwarz(Viol... Int J Oncol 2003-08-11

...Brca1 function. We report that Brca1-deficiency in p53-null cells was associated with increased sensitivity to the topoi...

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