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TP53 BRCA1 CRISPR single-cell cancer

Chen(Shou-Tung),Chen(Ruei-A),Kuo(Shou-Jen)... Breast Cancer Res Treat 2003-07-01

...BRCA1 gene has been shown to be strongly associated with the occurrence of familial breast cancer. The spectrum of BRCA1...

Goldberg(Michal),Stucki(Manuel),Falck(Jaco... Nature 2003-03-28

...BRCA1 carboxy-terminal (BRCT) domains, as a binding partner for the MRE11 complex. We show that, in response to ionizing...

Stewart(Grant S),Wang(Bin),Bignell(Colin R... Nature 2003-03-28

...BRCA1 carboxy-terminal (BRCT) and forkhead-associated (FHA) domain-containing protein, MDC1 (mediator of DNA damage chec...

Lee(Wen-Ying) Appl Immunohistochem Mol Mo... 2003-04-07

...BRCA1, were determined by immunohistochemistry. Comparisons of the distribution of these parameters in three age groups ...

Wojciechowska-Lacka(A),Markowska(J),Skasko... Eur J Gynaecol Oncol 2003-07-22

...BRCA1 mutation, and in 35 patients with Stage III sporadic ovarian tumors.,Progressive disease within first six months f...

Abramovitch(Shirley),Glaser(Tova),Ouchi(To... FEBS Lett 2003-05-15

...BRCA1 is a transcription factor involved in numerous cellular processes, including DNA damage repair, cell growth, and a...

Montagna(Marco),Dalla Palma(Maurizia),Meni... Hum Mol Genet 2003-12-18

...BRCA1 mutation, and 15 were previously shown to carry a mutation in either the BRCA2 (five families) or BRCA1 gene (10 f...

Benezra(Miriam),Chevallier(Nathalie),Morri... J Biol Chem 2003-08-27

BRCA1 is a tumor suppressor gene mutated in cases of hereditary breast and ovarian cancer. BRCA1 protein is involved in ...

Pastore(Giovanna),Canadè(Adolfo),Costantin... Rays 2003-05-01

...BRCA1 and BRCA2) have already been identified. At present, genetic tests to identify known inherited mutations associate...

Llorca(O),Rivera-Calzada(A),Grantham(J),Wi... Oncogene 2003-07-24

...BRCA1 and H2AX. ATM is probably a component of, or in close proximity to, the double-stranded DNA break-sensing machiner...

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