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Heterogeneous activation of the Fanconi anemia pathway by patient-derived FAN...

Adachi(Daiki),Oda(Tsukasa),Yagasaki(Hirosh... Hum Mol Genet 2003-05-19

...BRCA1 machinery, affects cellular response to DNA damage. However, the role of the FA pathway in defective DNA damage re...

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domai...

Kobayashi(Junya),Tauchi(Hiroshi),Sakamoto(... Curr Biol 2003-05-01

...BRCA1. Furthermore, this NBS1 physical interaction was reduced when anti-gamma-H2AX antibody was introduced into normal ...

HER-2/neu status and tumor morphology of invasive breast carcinomas in Ashken...

Quenneville(Louise A),Phillips(Kelly-Anne)... Cancer 2003-01-31

...BRCA1 mutation status is known.,Thirty-eight tumors from 32 BRCA1 carriers and 354 tumors from 334 noncarriers were anal...

Chromosome breakage syndromes and cancer.

Duker(Nahum J) Am J Med Genet 2003-05-09

...BRCA1 and BRCA2 genes. The cloning of the encoding genes and the characterization of their products have resulted in par...

Two approaches to mutation detection based on functional data.

Pfeiffer(Ruth M),Bura(Efstathia),Smith(Ame... Stat Med 2003-03-14

...BRCA1 and test the performance of the methods on independent samples.

Risk factors for ovarian cancer and early-onset breast cancer in Mongolia.

Elit(L),Baigal(G),Jack(E),Munkhtaivan(A),N... Eur J Gynaecol Oncol 2003-03-07

To determine if there are founder BRCA1 mutations in the Mongolian population.,Seventeen women with ovarian cancer, 14 w...

Expression of a truncated Brca1 protein delays lactational mammary developmen...

Brown(Melissa A),Nicolai(Hans),Howe(Kathy)... Transgenic Res 2003-04-28

...BRCA1 have biological activity in vivo, we have expressed a truncated Brca1 protein (trBrca1) in cell-lines and in the m...

The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origi...

Van Hatten(Ruth A),Tutter(Antonin V),Holwa... J Cell Biol 2003-01-17

...BRCA1 COOH terminus repeat-containing Xmus101 protein is required for loading of Cdc45 onto the origin. Xmus101 chromati...

Comparison of techniques for the successful detection of BRCA1 mutations in f...

Bernstein(Jonine L),Thompson(W Douglas),Ca... Cancer Epidemiol Biomarkers... 2003-02-25

...BRCA1 gene mutation detection. The probability of detecting sequencing artifacts was also investigated. We found that: (...

Progress of a Comprehensive Familial Cancer Genetic Counseling Program in the...

Hartenbach(Ellen M),Becker(Joanne M),Grose... Genet Test 2003-03-06

BRCA1 and BRCA2 mutation carriers have an increased risk of developing breast and/or ovarian cancer. Technical advances ...

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