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TP53 BRCA1 CRISPR single-cell cancer

Nieto(A),Pérez-Alenza(M D),Del Castillo(N)... J Comp Pathol 2003-07-15

BRCA1 is a nuclear phosphoprotein that participates in the regulation of the cell cycle. The role of the BRCA1 gene in c...

McCarthy(Ellen E),Celebi(Julide T),Baer(Ri... Mol Cell Biol 2003-08-14

...Brca1-null, and double Bard1; Brca1-null mice provide strong genetic evidence that the developmental functions of Brca1 ...

Nixon(R M),Duffy(S W) J Cancer Epidemiol Prev 2003-08-05

...BRCA1 or BRCA2 gene. These mutations confer a substantially increased risk of breast cancer. These are also published ra...

de Sanjosé(Silvia),Léoné(Mélanie),Bérez(Vi... Int J Cancer 2003-09-09

...BRCA1 and BRCA2 mutations. Nine of the 136 (6.6%) were found to carry BRCA deleterious mutations (MUT) (1 BRCA1 and 8 BR...

Yamane(Kazuhiko),Chen(Junjie),Kinsella(Tim... Cancer Res 2003-07-28

...BRCA1. We report that, when expression of TopBP1 protein is inhibited in BRCA1 mutant cells, mimicking a TopBP1, BRCA1 d...

Corde(Stéphanie),Balosso(Jacques),Elleaume... Cancer Res 2003-07-28

...BRCA1 protein, and activation of proto-oncogenic c-Abl tyrosine kinase.

Franchitto(Annapaola),Oshima(Junko),Pichie... Cancer Res 2003-07-28

...BRCA1 is phosphorylated in an ATR-dependent manner in response to decatenation checkpoint activation and that this phosp...

Thorstenson(Yvonne R),Roxas(Adriane),Krois... Cancer Res 2003-07-28

...BRCA1 and BRCA2 mutations, 137 different sequence alterations of ATM were identified. Seven of these were mutations pres...

Sliwerska(Elzbieta),Szpecht-Potocka(Agnies... Med Wieku Rozwoj 2003-08-01

...BRCA1 genes.

de la Hoya(M),Díez(O),Pérez-Segura(P),Godi... J Med Genet 2003-08-05

To test whether statistical models developed to calculate pre-test probability of being a BRCA1/2 carrier can differenti...

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