...BRCA1 or MLH1 were analysed. NBS- and hMRE11-deficient cells present a classical kinetic of NF-kappaB induction after ca...
...BRCA1/2 carriers and non-carriers with ovarian cancer. However, the effects of tubal ligation may differ between BRCA1 c...
...BRCA1-associated tumors. A high level of BRCA1 promoter hypermethylation was detected, suggesting a possible role of thi...
...BRCA1 and that LMO4 can repress its transcriptional activity. Since proto-oncogene deregulation can result from activati...
...BRCA1 and BRCA2 (refs. 1,2). A key step in this pathway is monoubiquitination of FANCD2, resulting in the redistribution...
...BRCA1 germline mutations. The presence of GMP may influence treatment decisions.
Germline mutations of the breast cancer predisposing known genes, BRCA1 and BRCA2, with an autosomal dominant transmissi...
...BRCA1 is not accompanied by underlying mutation of the gene in tumor cells with loss of heterozygosity for the BRCA1 gen...
...BRCA1/BARD1 are not known, BRCA1 autoubiquitination occurs principally by conjugation with K6-linked polymers. The abili...
Germline mutations of the BRCA1 gene predispose individuals mainly to the development of breast and/or ovarian cancer. H...
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