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Expression of BRCA1 and BRCA2 in different tumor cell lines with various grow...

Vissac(Cécile),Peffault De Latour(Monique)... Clin Chim Acta 2002-07-24

BRCA1 and BRCA2 are breast cancer susceptibility genes. Recent studies suggest that BRCA1 interacts with a great variety...

Characterization of the c-MYC-regulated transcriptome by SAGE: identification...

Menssen(Antje),Hermeking(Heiko) Proc Natl Acad Sci U S A 2002-06-11

...BRCA1, MSH2, and APEX were induced by c-MYC, suggesting that c-MYC couples DNA replication to processes preserving the i...

Loss of heterozygosity analysis at the BRCA loci in tumor samples from patien...

Osorio(Ana),de la Hoya(Miguel),Rodríguez-L... Int J Cancer 2002-06-13

...BRCA1 and BRCA2 genes are responsible for a high proportion of familial breast cancer; germline mutations in these genes...

[Genetic test and prophylactic treatment in breast cancer families].

Miyoshi(Yasuo),Noguchi(Shinzaburo) Gan To Kagaku Ryoho 2002-05-16

...BRCA1, and BRCA2 genes among 113 Japanese breast cancer families. We found a BRCA1 codon 63 (nucleotide 307) nonsense mu...

Transitional cell ovarian carcinoma in a BRCA1 mutation carrier.

Rao(Gautam G),Ashfaq(Raheela),Schorge(John O) Obstet Gynecol 2002-09-17

BRCA1 mutation carriers are at high risk of developing epithelial ovarian cancer, but the transitional cell variant has ...

Caspase-3 mediated cleavage of BRCA1 during UV-induced apoptosis.

Zhan(Qimin),Jin(Shunqian),Ng(Bobby),Pliske... Oncogene 2002-08-30

...BRCA1 level is downregulated during UV-induced apoptosis by caspase-3 mediated cleavage. Cleavage of BRCA1 by caspase-3 ...

Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic i...

Weaver(Zoë),Montagna(Cristina),Xu(Xiaoling... Oncogene 2002-08-16

BRCA1 mutation carriers have an increased susceptibility to breast and ovarian cancer. Excision of exon 11 of Brca1 in t...

Targeted substrate degradation by an engineered double RING ubiquitin ligase.

Oyake(Daisuke),Nishikawa(Hiroyuki),Koizuka... Biochem Biophys Res Commun 2002-08-29

...BRCA1 and BARD1 linked to a substrate recognition site PCNA, which is known to interact with cyclin-dependent kinase inh...

Mutation analysis of the BRCA1 gene in Malaysian breast cancer patients.

Balraj(P),Khoo(A S B),Volpi(L),Tan(J A M A... Singapore Med J 2002-10-16

...BRCA1). Direct sequencing of the entire coding region of BRCA1 identified a frameshift mutation, c.5447-5448insC (insC54...

Ovarian tumors associated with multiple endocrine neoplasias and related synd...

Papageorgiou(T),Stratakis(C A) Int J Gynecol Cancer 2002-09-26

...BRCA1 and BRCA2, have been implicated), little is known about the presence of ovarian tumors and cancer in women already...

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