...NF1) mutation, suggesting potential mechanisms of acquired resistance. An analysis of adverse events indicated manageabl...
...NF1::ADAP, FGFR2::POC1B, and RB1:TTTY3, respectively. In 2 patients with PDA-C, PDA was eradicated in transurethral rese...
...NF1/FGFR, and HER2 amplification; 'negatively hyper-selected' cases) had 78.1% ORR compared with 54.5% ORR for patients ...
...NF1 gene encoding for the neurofibromin protein, a tumor suppressor that prevent cells from uncontrolled proliferation. ...
...NF1 mut/loss had a significantly higher T/N ratio on their FDG-PET images compared with those without these alterations....
...Nf1 tumor suppressor genes (BPRN-het and BPRN-homo mice, respectively). Mice received hormones or placebo via slow-relea...
...NF1 mutations) were present in 10 of 15 patients and overrepresented in the HGG-like group (3/5) compared with previousl...
...NF1-null malignant peripheral nerve sheath tumors (MPNSTs). However, MPNSTs variably express multiple erbB receptors wit...
...NF1 (n = 1), RAD51D (n = 1), and CDKN2A (n = 1). MPM index cases were more likely to carry a deleterious mutation than c...
...NF1, PIK3CA, and RET, while only 62% were captured in plasma cfDNA. PE-cfDNA also has the highest detection rate of EGFR...
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