...NF1, SMARCA4, and RET (P<0.05). Transcriptomic analysis demonstrated upregulation of immune-related genes (CCL21, CXCL2)...
...NF1 and DICER. We identified approximately 11% of UTUC cases as suspected LS and at least 1.4% patients with confirmed L...
...NF1, CYLD, and SDHB. Variants of uncertain significance represented 66.7% of all detected variants and affected several ...
...NF1 actionable mutations. Cabozantinib conferred radiographic partial response in two patients harboring a MET and a PDG...
...NF1, ARID1A, BRCA1, and PTEN) were used to stratify the cohort into the following three subgroups: patients with tumors ...
...NF1 (64%), ATRX (52%), PTPN11 (28%), FGFR1/FGFR4 (20%), TERTp (16%), and TP53 (16%). Patients with HGAP had significantl...
...NF1, DICER1, SMARCA4, PTEN, and PIK3CA, were also detected. Importantly, molecular profiling had significant diagnostic ...
...NF1, RET and BRCA2 genes. In 61.9% (13/21) of positive cases, an identified cancer predisposition syndrome was linked to...
...NF1, and CHEK2) and deciphered the functional consequences leveraging the higher throughput Illumina NovaSeq X and NextS...
...NF1 (64.3%, 18/28), along with activating mutations in PDGFRA (39.3%, 11/28) and EGFR (32.1%, 9/29), suggesting tumor pr...
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