Being a female with a germline BRCA1 or BRCA2 pathogenic variant (PV) elevates risks of developing breast and ovarian ca...
...BRCA1-associated protein 1 (BAP1) or methylthioadenosine phosphorylase (MTAP) loss of expression, and absence of stromal...
...BRCA1 and E2F1. This work provides resources for understanding testicular senescence and nominates ZFX and CXCL13 as pot...
BRCA1/2 founder mutation have been detected in various populations and ethnicities. Molecular diagnosis of HBOC remains ...
...BRCA1, CCNA2 and CDK1 might be vital m6A-related mRNAs, and VCAM1 and RAP1A may be the most important two. A few crucial...
...BRCA1 and BRCA2, are primarily responsible for inherited breast cancers, while mutations in moderate-risk genes also inc...
...BRCA1-A DNA damage repair complex, suggesting a USP7-TOPORS-BRCA1-A axis that might further explain the continued prolif...
...BRCA1, BRCA2, FBN1, ATM, PALB2, MYH7, USH2A, and PAH), achieving Leave-One-Out Cross-Validation (LOO-CV) MCC of 0.895-0....
...BRCA1-mutant models. In contrast, strategies aimed at restoring homologous recombination exhibited strong in vitro syner...
...BRCA1/2 status, homologous recombination deficiency (HRD), tumor-infiltrating lymphocytes (TILs), Ki-67, intrinsic molec...
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