...BRCA1. A significant number of BRCA1-linked familial breast cancer patients, however, have no detectable BRCA1 mutation....
...BRCA1 or BRCA2. Here we report two families of aboriginal descent both with the same BRCA1 alterations (1510insG, 1506A>...
...BRCA1 and BRCA2 are associated with a hereditary disposition to breast cancer, and the algorithm is used to find gene se...
...BRCA1 and BRCA2 mutations, although preliminary evidence favors benefit for at least those with a BRCA2 mutation. Raloxi...
...BRCA1/2 mutation. This is the first large multi-centre study of this population in the UK. The study evaluates mental he...
...BRCA1 predispose individuals to breast and ovarian cancers. We observed a novel endogenous association of BRCA1 with Nmi...
...BRCA1 or BRCA2 genes develop their cancers earlier in life (during the premenopausal period), 75-80% of all breast cance...
...BRCA1 either after stalled replication forks or gamma-rays. We also provide evidence that BLM is phosphorylated after re...
...BRCA1 and BRCA2 account for 60-70% of these hereditary breast cancers. The chromosomal location of BRCA1 is 17q21 and th...
...Brca1 mutant in ID-8 cells which contain two endogenous wild-type Brca1 alleles led to a dominant-negative effect of Brc...
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