...BRCA1 and BRCA2), the proportion of affected probands diagnosed with breast cancer before age 50 years and who have no f...
...BRCA1-Deltaex5 (isoform with an in frame skip of exon 5) ratio to the total BRCA1 expression level. IVS5+3A>G results in...
...BRCA1 allele, and the third showed loss of heterozygosity for BRCA1 but not BRCA2. The observation that breast tumors ar...
...BRCA1 caused by inherited mutation and tissue-specific somatic mutation leads to breast and ovarian cancer. Nearly all B...
...BRCA1 genes from primates, and the phytochrome (PHY) gene family in angiosperms. Positive selection is detected in the l...
...BRCA1 and BRCA2 in the homologous recombination repair (HRR) of double-strand breaks in DNA implicates this pathway in t...
...BRCA1 or BRCA2 mutations identified during a six-year period were offered enrollment in a prospective follow-up study. A...
...BRCA1 or BRCA2 mutations are limited. We investigated whether this procedure reduces the risk of cancers of the coelomic...
...BRCA1 and c-Abl. We show that the C terminus of BRCA1 is phosphorylated by c-Abl in vitro. In vivo, BRCA1 is phosphoryla...
...BRCA1 can regulate p53-dependent transcription. Because BRCA1 overexpression stabilizes wild-type p53 but does not lead ...
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