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TP53 BRCA1 CRISPR single-cell cancer

Foulkes(W D),Rosenblatt(J),Chappuis(P O) J Mammary Gland Biol Neoplasia 2002-06-17

...BRCA1 and BRCA2, which from a population perspective are much more important than TP53. Other rarer genes have subsequen...

Nathanson(Katherine L),Shugart(Yin Y),Omar... Hum Mol Genet 2002-10-10

...BRCA1 mutation has been observed, suggesting that modifiers of BRCA1 penetrance may exist. We hypothesized that the modi...

Berry(Donald A),Iversen(Edwin S),Gudbjarts... J Clin Oncol 2002-06-20

...BRCA1 and BRCA2. Genetic testing for BRCA1 and BRCA2 is highly sensitive, missing an estimated 15% of mutations. In the ...

Zhong(Qing),Chen(Chi-Fen),Chen(Phang-Lang)... J Biol Chem 2002-09-09

...Brca1(+/+):p53(-/-) or Brca1(-/-):p53(-/-). The Brca1(-/-):p53(-/-) MEFs appear to be extremely sensitive to ionizing ra...

Leeper(Katherine),Garcia(Rochelle),Swisher... Gynecol Oncol 2002-12-16

...BRCA1 and BRCA2 genes or had family history suggestive for ovarian and breast cancer susceptibility.,Thirty women with e...

Williamson(Elizabeth A),Dadmanesh(Farnaz),... Oncogene 2002-07-23

...BRCA1. BRCA1 has a number of activities including DNA repair, growth inhibition and as a transcription factor. Here we d...

Hu(Yan-Fen),Li(Rong) Genes Dev 2002-07-19

...BRCA1, stimulates transcription in a cell context-dependent manner. Here, it is shown that BRCA1 interacts with Jun prot...

Tereshchenko(I V),Béshém(V M),Slonimskaia(... Vopr Onkol 2002-07-22

The proportion of BRCA1/2 genes varies widely among populations. We investigated 52 cases of breast cancer: 24 cases of ...

Einbeigi(Zakaria),Meis-Kindblom(Jeanne M),... Acta Oncol 2002-07-29

...BRCA1 and BRCA2 gene mutations. These results suggest that genetic factors account for the excess in ovarian cancer that...

Manderson(Emily N),Presneau(Nadège),Proven... Mol Carcinog 2002-07-31

...BRCA1 locus (P = 0.014). LOH of chromosome 3p was noted in four specimens that did not display LOH of either the BRCA1 o...

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