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TP53 BRCA1 CRISPR single-cell cancer

Irminger-Finger(Irmgard),Leung(Wai Choi) Int J Biochem Cell Biol 2002-09-05

...BRCA1)-associated RING domain (BARD1) was discovered as a protein interacting with the RING domain of BRCA1. It is struc...

van Roosmalen(Mariëlle S),Verhoef(Lia C G)... J Clin Oncol 2002-04-30

BRCA1 mutation carriers have a high risk of developing breast and ovarian cancer. Carriers may opt for prophylactic surg...

Miyamoto(Kazuaki),Fukutomi(Takashi),Asada(... Jpn J Clin Oncol 2002-04-23

...BRCA1 is well known to cause familial breast cancer. Although somatic mutations of the BRCA1 gene are rare in sporadic b...

Celeste(Arkady),Petersen(Simone),Romanienk... Science 2002-05-30

...Brca1, but not Rad51, to irradiation-induced foci. Thus, H2AX is critical for facilitating the assembly of specific DNA-...

Campos(B),Diez(O),Domènech(M),Baena(M),Per... Ann Oncol 2002-08-09

...BRCA1 mutations and 25%-35% BRCA2 mutations. However, these percentages could have been overestimated and likely vary am...

Sullivan(Alexandra),Yuille(Martin),Repelli... Oncogene 2002-03-07

...BRCA1-associated breast cancers, 1/78 sporadic breast cancers and 2/25 typical medullary carcinomas. Each of the BRCA1-a...

Baldeyron(Céline),Jacquemin(Emilie),Smith(... Oncogene 2002-03-07

...BRCA1(+/-) cell lines in comparison to two control cell lines. Moreover, cell-free BRCA1(+/-) extracts are unable to pro...

Johnson(Suzanne M),Shaw(Jacqueline A),Walk... Int J Cancer 2002-03-07

...BRCA1) and 13q12-13 (BRCA2) using polymerase chain reaction analysis of polymorphic microsatellite markers. These were c...

Digweed(Martin),Rothe(Susanne),Demuth(Ilja... Carcinogenesis 2002-08-30

...BRCA1 for visualisation. IR induced foci detected with anti-RAD51, but not those detected with anti-MRE11, are reduced i...

An(Qian),Liu(Yong),Gao(Yanning),Huang(Jinf... Cancer Lett 2002-10-23

...BRCA1, DPC4 and DCC. Our data demonstrated frequent allelic losses of FHIT, p53, IFNA, VHL and p16 in both SCC and ADC. ...

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