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Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA dou...

Loke(Johnny),Pearlman(Alexander),Upadhyay(... Hum Mol Genet 2016-02-16

...BARD1, PALB2, BRCA2 and FANCD2, phosphorylation of p53 or BRCA1 nuclear localization in response to DNA damage caused by...

Ubiquitin in regulation of spindle apparatus and its positioning: implication...

Srivastava(Devika),Chakrabarti(Oishee) Biochem Cell Biol 2016-05-16

...BARD1, MGRN1, SMURF2, and SIAH1; these play a pivotal role in the correct positioning of the spindle apparatus. A direct...

Dynamic interplay between locus-specific DNA methylation and hydroxymethylati...

Kamdar(Shivani N),Ho(Linh T),Kron(Ken J),I... Clin Epigenetics 2016-04-22

...BARD1 signaling and steroid hormone receptor signaling in cancer. We confirm a modest correlation of hydroxymethylation ...

The BARD1/HP1 interaction: Another clue to heterochromatin involvement in hom...

Fukuda(Takayo),Tsuruga(Tomoko),Kuroda(Taka... Mol Cell Oncol 2016-06-16

...BARD1/HP1 interaction, required for the retention of BRCA1, CTIP, and RAD51 at DSB sites, may play a critical role in th...

The BRCA1 variant p.Ser36Tyr abrogates BRCA1 protein function and potentially...

Christou(Charita M),Hadjisavvas(Andreas),K... PLoS One 2015-01-20

...BARD1. Further, co-precipitation analysis of nuclear and cytosolic extracts as well as immunofluorescence studies showed...

Characterization of an Italian founder mutation in the RING-finger domain of ...

Caleca(Laura),Putignano(Anna Laura),Colomb... PLoS One 2015-01-13

...BARD1, in a similar way as proven deleterious mutations in the RING-domain. Overall, 55 of 83 (66%) female mutation carr...

Characterization of LGALS3 (galectin-3) as a player in DNA damage response.

Carvalho(Renato S),Fernandes(Vanessa C),Ne... Cancer Biol Ther 2015-02-13

...BARD1, the main partner of breast and ovarian cancer susceptibility gene product BRCA1, both involved in HR pathway. In ...

KSR1 regulates BRCA1 degradation and inhibits breast cancer growth.

Stebbing(J),Zhang(H),Xu(Y),Lit(L C),Green(... Oncogene 2015-07-27

...BARD1) and checkpoint kinase 1 (Chk1) levels. Phospho-profiling of major components of the canonical Ras-RAF-mitogen-act...

Alternative splicing in cancer: implications for biology and therapy.

Chen(J),Weiss(W A) Oncogene 2015-03-10

...BARD1 and AR to illuminate roles for alternative splicing in cancer. We also examine the intersection between alternativ...

Next-generation sequencing for the diagnosis of hereditary breast and ovarian...

Castéra(Laurent),Krieger(Sophie),Rousselin... Eur J Hum Genet 2015-06-25

...BARD1, 1/468 in PMS1 and 1/468 in MLH3. These results demonstrate the efficiency of NGS in performing molecular diagnosi...

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