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Di Costanzo(F),Williamson(J),Robson(CN),Ga... Mol Cancer Ther 2026-04-02

...BRCA1 or BRCA2 gene mutations, whereas their role in tumors with alterations of DNA repair genes other than BRCA1/2 and ...

García-Díaz(HC),Gómez-Alonso(J),Rabuñal-Ál... J Chemother 2026-03-09

...BRCA1/2, may benefit from olaparib. Although the phase III POLO trial demonstrated improved progression-free survival (P...

Mashal(S),Melanson(A),Apostolova(C),Ferrou... Ann Surg Oncol 2026-06-00

...BRCA1/2, there remains a paucity of data regarding variations in uptake by ethnicity. We conducted a retrospective cohor...

Chung(OW),Yao(S),Wang(L),Yang(F),Schier(L)... Proc Natl Acad Sci U S A 2026-03-17

...BRCA1-A and the LIG4 complexes as key drivers of ecDNA production. Following DNA segmentation, the upstream BRCA1-A comp...

Dencker(C),Strehlow(V),Aktas(B),Lemke(J),H... Hered Cancer Clin Pract 2026-03-12

...BRCA1, which also increases ovarian cancer risk and, in men, prostate cancer risk. BRCA1 variants are typically autosoma...

Kawahara(S),Taki(M),Hamanishi(J),Ebara(S),... Mol Cancer Ther 2026-03-12

...BRCA1 and BRCA2, induced apoptosis and DNA damage, and inhibited tumor growth in USC PDX models with high CDK12 expressi...

Saule(C),Laas(E),Weber(N),Bataillon(G),Bec... Gynecol Oncol 2026-05-00

Women with inherited susceptibility or a strong family history of ovarian cancer, particularly carriers of pathogenic BR...

Nahshon(C),Assaf(W),Fahoum(L),Regev-Sadeh(... Maturitas 2026-05-00

...BRCA1/2 pathogenic variant who had previously undergone risk-reducing salpingo-oophorectomy with or without concomitant ...

Laitman(Y),Zalmanoviz(S),Netzer(I),Bernste... Cancer Genet 2026-06-00

...BRCA1, BRCA2, MSH2, and MSH6 genes, has not been reported. Individuals who underwent MGPT after oncogenetic counseling b...

Hu(L),Ma(X),Cai(X),Yan(T),Zhou(K),Shan(C),... Cell Discov 2026-03-12

BRCA1-deficient epithelial ovarian cancer (EOC) is reported to respond to poly (adenosine diphosphate-ribose) polymerase...