de Massy(Bernard) Annu Rev Genet 2014-04-14

...SPO11 protein, assisted by several other factors. Some of them are absolutely required, whereas others are needed only f...

Eldai(Hisham),Periyasamy(Sathish),Al Qarni(S… PLoS One 2014-08-04

...SPO11, ZNF217, PLEKHA8, HOXA3, GPNMB, IGF2BP3 and PCAT1) as novel in their association with CRC. Pathway and target pred...

Gray(Stephen),Allison(Rachal M),Garcia(Valer… Open Biol 2014-01-07

...Spo11 is the evolutionarily conserved catalytic subunit. Precisely how Spo11 and its accessory proteins function or are ...

Feretzaki(Marianna),Heitman(Joseph) PLoS Genet 2014-03-21

...Spo11, and Ubc5. Spo11 and Ubc5 promote sporulation during both bisexual and unisexual reproduction. Genetic and phenoty...

Biswas(Uddipta),Wetzker(Cornelia),Lange(Juli… PLoS Genet 2014-08-20

...SPO11 and thus of programmed double-strand breaks. These breaks are properly generated in Smc1β⁻/⁻ spermatocytes, but th...

Ray(Sreerupa),Menezes(Miriam Rose),Senejani(… Yale J Biol Med 2014-08-13

...Spo11 complex from the 5' ends of double-strand breaks. Studies with Pol ß mutant mice are currently being undertaken to...

Baryshnikova(Anastasia),VanderSluis(Benjamin… G3 (Bethesda) 2014-06-23

...Spo11-catalyzed DNA double-strand breaks. Given that crossovers too near or too far from centromeres are detrimental to ...

Ito(Masaru),Kugou(Kazuto),Fawcett(Jeffrey A)… Genes Cells 2014-10-27

...Spo11 persists at Rec8 binding sites during DSB formation. Spo11 fused with Gal4 DNA binding domain (Gal4BD-Spo11) tethe...

Ishiguro(Kei-Ichiro),Kim(Jihye),Shibuya(Hiro… Genes Dev 2014-04-29

...Spo11 knockout spermatocytes, in which DSB-dependent DNA homology search is absent. Disruption of meiosis-specific cohes...

Baier(Brian),Hunt(Patricia),Broman(Karl W),H… PLoS Genet 2014-06-17

...Spo11 resulted in differences in the numbers of DSBs but not the number of MLH1 foci. Instead, chromatin conformation ap...