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Allen(S),Rowlands(CF),Garrett(A),Couch(F),... medRxiv 2026-05-17

...BRCA1, BRCA2, PALB2, ATM, CHEK2). A combined LLR was produced for 4,690 missense variants; 927 variants received evidenc...

Fields(N),Han(S),Mei(W),Shannon(E),Buehler... medRxiv 2026-05-13

...BRCA1 in breast cancer. Cancer polygenic risk scores were enriched in cases and correlated with patterns of cancer diagn...

Jordan(MR),Kersey(JL),Garrett(JE),Liu(S),W... bioRxiv 2026-05-13

...BRCA1-deficient MDA-MB-436 triple negative breast cancer (TNBC) cells using a selection strategy of high-level dosing co...

Finch(M),Booth(C),Frank(S),Patel(A),Sagoo(... J Oncol Pharm Pract 2026-05-25

...BRCA1 and 2) positive, human epidermal growth factor receptor 2 (HER2)-negative, high-risk early disease after chemother...

Sumii(R),Omote(S),Omote(R),Fujita(I),Toyok... Clin J Gastroenterol 2026-08-00

...BRCA1/2 and mismatch repair (MMR) genes have distinct therapeutic implications. However, concurrent germline variants in...

Morganti(S),Kim(SE),Jin(Q),Cha(J),Zeigler(... JNCI Cancer Spectr 2026-07-07

...BRCA1/2 (gBRCA1/2)-associated breast cancer differ compared with sporadic tumors is controversial. We explored the impac...

Sharma(S),Wong(HY),Johnston(RL),Koufarioti... BMC Cancer 2026-05-25

...BRCA1, BRCA2, CCNE1, CDKN2A, EGFR, KRAS, MDM2, PIK3CA, PTEN, SMARCB1 and TSC2. Candidate co-occurring alterations includ...

Cavarzerani(E),Caligiuri(I),Bartoletti(M),... J Adv Res 2026-05-00

...BRCA1 mutation exhibited resistance to Carboplatin and PARP inhibitors, reflecting the clinical scenario and reinforcing...

Marhamati(S),Jalili(H),Ziamajidi(N),Bahman... Iran Biomed J 2026-09-10

...BRCA1 were quantified using RT‑qPCR, and BRCA1 protein levels were determined using Western blotting. GEPIA, STRING, and...

Das(PR),Rahman(MJ),Nirob(SR),Patwary(MO),I... Front Oncol 2026-00-00

...BRCA1/PARP, as benchmarks for GNN-based discovery frameworks. Despite encouraging progress, current evidence remains lar...